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Loss of Stromal IMP1 Promotes a Tumorigenic Microenvironment in the Colon.
Hamilton KE, Chatterji P, Lundsmith ET, Andres SF, Giroux V, Hicks PD, Noubissi FK, Spiegelman VS, Rustgi AK. Hamilton KE, et al. Mol Cancer Res. 2015 Nov;13(11):1478-86. doi: 10.1158/1541-7786.MCR-15-0224. Epub 2015 Jul 20. Mol Cancer Res. 2015. PMID: 26194191 Free PMC article.
Multiple Gastrointestinal Polyps in Patients Treated with BRAF Inhibitors.
Amaravadi RK, Hamilton KE, Ma X, Piao S, Portillo AD, Nathanson KL, Carlino MS, Long GV, Puzanov I, Xu X, Morrissette JJ, Tsai KY, Flaherty KT, Sosman JA, Goodman GR, McArthur GA, Rustgi AK, Metz DC, Schuchter LM, Chapman PB, Sepulveda AR. Amaravadi RK, et al. Among authors: hamilton ke. Clin Cancer Res. 2015 Dec 1;21(23):5215-21. doi: 10.1158/1078-0432.CCR-15-0469. Epub 2015 Jul 22. Clin Cancer Res. 2015. PMID: 26202952 Free PMC article.
Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration.
Giroux V, Lento AA, Islam M, Pitarresi JR, Kharbanda A, Hamilton KE, Whelan KA, Long A, Rhoades B, Tang Q, Nakagawa H, Lengner CJ, Bass AJ, Wileyto EP, Klein-Szanto AJ, Wang TC, Rustgi AK. Giroux V, et al. Among authors: hamilton ke. J Clin Invest. 2017 Jun 1;127(6):2378-2391. doi: 10.1172/JCI88941. Epub 2017 May 8. J Clin Invest. 2017. PMID: 28481227 Free PMC article.
Differential Regulation of LET-7 by LIN28B Isoform-Specific Functions.
Mizuno R, Chatterji P, Andres S, Hamilton K, Simon L, Foley SW, Jeganathan A, Gregory BD, Madison B, Rustgi AK. Mizuno R, et al. Mol Cancer Res. 2018 Mar;16(3):403-416. doi: 10.1158/1541-7786.MCR-17-0514. Epub 2018 Jan 12. Mol Cancer Res. 2018. PMID: 29330293 Free PMC article.
The Esophageal Organoid System Reveals Functional Interplay Between Notch and Cytokines in Reactive Epithelial Changes.
Kasagi Y, Chandramouleeswaran PM, Whelan KA, Tanaka K, Giroux V, Sharma M, Wang J, Benitez AJ, DeMarshall M, Tobias JW, Hamilton KE, Falk GW, Spergel JM, Klein-Szanto AJ, Rustgi AK, Muir AB, Nakagawa H. Kasagi Y, et al. Among authors: hamilton ke. Cell Mol Gastroenterol Hepatol. 2018 Jan 3;5(3):333-352. doi: 10.1016/j.jcmgh.2017.12.013. eCollection 2018 Mar. Cell Mol Gastroenterol Hepatol. 2018. PMID: 29552622 Free PMC article.
Mouse Intestinal Krt15+ Crypt Cells Are Radio-Resistant and Tumor Initiating.
Giroux V, Stephan J, Chatterji P, Rhoades B, Wileyto EP, Klein-Szanto AJ, Lengner CJ, Hamilton KE, Rustgi AK. Giroux V, et al. Among authors: hamilton ke. Stem Cell Reports. 2018 Jun 5;10(6):1947-1958. doi: 10.1016/j.stemcr.2018.04.022. Epub 2018 May 24. Stem Cell Reports. 2018. PMID: 29805107 Free PMC article.
The LIN28B-IMP1 post-transcriptional regulon has opposing effects on oncogenic signaling in the intestine.
Chatterji P, Hamilton KE, Liang S, Andres SF, Wijeratne HRS, Mizuno R, Simon LA, Hicks PD, Foley SW, Pitarresi JR, Klein-Szanto AJ, Mah AT, Van Landeghem L, Gregory BD, Lengner CJ, Madison BB, Shah P, Rustgi AK. Chatterji P, et al. Among authors: hamilton ke. Genes Dev. 2018 Aug 1;32(15-16):1020-1034. doi: 10.1101/gad.314369.118. Genes Dev. 2018. PMID: 30068703 Free PMC article.
75 results