Gardner A - Search Results

1

The Link between Inactivation and High-Affinity Block of hERG1 Channels.

Wu W, Gardner A, Sanguinetti MC. Wu W, et al. Among authors: gardner a. Mol Pharmacol. 2015 Jun;87(6):1042-50. doi: 10.1124/mol.115.098111. Epub 2015 Apr 8. Mol Pharmacol. 2015. PMID: 25855787 Free PMC article.

2

Structural basis of ion permeation gating in Slo2.1 K+ channels.

Garg P, Gardner A, Garg V, Sanguinetti MC. Garg P, et al. Among authors: gardner a. J Gen Physiol. 2013 Nov;142(5):523-42. doi: 10.1085/jgp.201311064. J Gen Physiol. 2013. PMID: 24166878 Free PMC article.

3

Stoichiometry of altered hERG1 channel gating by small molecule activators.

Wu W, Sachse FB, Gardner A, Sanguinetti MC. Wu W, et al. Among authors: gardner a. J Gen Physiol. 2014 Apr;143(4):499-512. doi: 10.1085/jgp.201311038. Epub 2014 Mar 17. J Gen Physiol. 2014. PMID: 24638994 Free PMC article.

4

Cooperative subunit interactions mediate fast C-type inactivation of hERG1 K+ channels.

Wu W, Gardner A, Sanguinetti MC. Wu W, et al. Among authors: gardner a. J Physiol. 2014 Oct 15;592(20):4465-80. doi: 10.1113/jphysiol.2014.277483. Epub 2014 Jul 25. J Physiol. 2014. PMID: 25063820 Free PMC article.

5

Concatenated hERG1 tetramers reveal stoichiometry of altered channel gating by RPR-260243.

Wu W, Gardner A, Sanguinetti MC. Wu W, et al. Among authors: gardner a. Mol Pharmacol. 2015;87(3):401-9. doi: 10.1124/mol.114.096693. Epub 2014 Dec 17. Mol Pharmacol. 2015. PMID: 25519838 Free PMC article.

6

C-Linker Accounts for Differential Sensitivity of ERG1 and ERG2 K+ Channels to RPR260243-Induced Slow Deactivation.

Gardner A, Sanguinetti MC. Gardner A, et al. Mol Pharmacol. 2015 Jul;88(1):19-28. doi: 10.1124/mol.115.098384. Epub 2015 Apr 17. Mol Pharmacol. 2015. PMID: 25888115 Free PMC article.

7

Ginsenoside Rg3, a Gating Modifier of EAG Family K+ Channels.

Wu W, Gardner A, Sachse FB, Sanguinetti MC. Wu W, et al. Among authors: gardner a. Mol Pharmacol. 2016 Oct;90(4):469-82. doi: 10.1124/mol.116.104091. Epub 2016 Aug 8. Mol Pharmacol. 2016. PMID: 27502018 Free PMC article.

8

Molecular Basis of Altered hERG1 Channel Gating Induced by Ginsenoside Rg3.

Gardner A, Wu W, Thomson S, Zangerl-Plessl EM, Stary-Weinzinger A, Sanguinetti MC. Gardner A, et al. Mol Pharmacol. 2017 Oct;92(4):437-450. doi: 10.1124/mol.117.108886. Epub 2017 Jul 13. Mol Pharmacol. 2017. PMID: 28705808 Free PMC article.

9

Molecular mechanisms of Slo2 K⁺ channel closure.

Giese MH, Gardner A, Hansen A, Sanguinetti MC. Giese MH, et al. Among authors: gardner a. J Physiol. 2017 Apr 1;595(7):2321-2336. doi: 10.1113/JP273225. Epub 2016 Dec 2. J Physiol. 2017. PMID: 27682982 Free PMC article.

10

Identification of a domain that mediates association of platelet-activating factor acetylhydrolase with high density lipoprotein.

Gardner AA, Reichert EC, Topham MK, Stafforini DM. Gardner AA, et al. J Biol Chem. 2008 Jun 20;283(25):17099-106. doi: 10.1074/jbc.M802394200. Epub 2008 Apr 22. J Biol Chem. 2008. PMID: 18434304 Free PMC article.

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