Thoppil RJ - Search Results

1

Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy.

Adapala RK, Thoppil RJ, Ghosh K, Cappelli HC, Dudley AC, Paruchuri S, Keshamouni V, Klagsbrun M, Meszaros JG, Chilian WM, Ingber DE, Thodeti CK. Adapala RK, et al. Among authors: thoppil rj. Oncogene. 2016 Jan 21;35(3):314-22. doi: 10.1038/onc.2015.83. Epub 2015 Apr 13. Oncogene. 2016. PMID: 25867067 Free PMC article.

2

TRPV4 channels mediate cardiac fibroblast differentiation by integrating mechanical and soluble signals.

Adapala RK, Thoppil RJ, Luther DJ, Paruchuri S, Meszaros JG, Chilian WM, Thodeti CK. Adapala RK, et al. Among authors: thoppil rj. J Mol Cell Cardiol. 2013 Jan;54:45-52. doi: 10.1016/j.yjmcc.2012.10.016. Epub 2012 Nov 8. J Mol Cell Cardiol. 2013. PMID: 23142541 Free PMC article.

3

TRPV4 channel activation selectively inhibits tumor endothelial cell proliferation.

Thoppil RJ, Adapala RK, Cappelli HC, Kondeti V, Dudley AC, Gary Meszaros J, Paruchuri S, Thodeti CK. Thoppil RJ, et al. Sci Rep. 2015 Sep 21;5:14257. doi: 10.1038/srep14257. Sci Rep. 2015. PMID: 26388427 Free PMC article.

4

TRPV4 channels regulate tumor angiogenesis via modulation of Rho/Rho kinase pathway.

Thoppil RJ, Cappelli HC, Adapala RK, Kanugula AK, Paruchuri S, Thodeti CK. Thoppil RJ, et al. Oncotarget. 2016 May 3;7(18):25849-61. doi: 10.18632/oncotarget.8405. Oncotarget. 2016. PMID: 27029071 Free PMC article.

5

Disruption of TRPV1-mediated coupling of coronary blood flow to cardiac metabolism in diabetic mice: role of nitric oxide and BK channels.

Guarini G, Ohanyan VA, Kmetz JG, DelloStritto DJ, Thoppil RJ, Thodeti CK, Meszaros JG, Damron DS, Bratz IN. Guarini G, et al. Among authors: thoppil rj. Am J Physiol Heart Circ Physiol. 2012 Jul 15;303(2):H216-23. doi: 10.1152/ajpheart.00011.2012. Epub 2012 May 18. Am J Physiol Heart Circ Physiol. 2012. PMID: 22610171 Free article.

6

Pomegranate phytoconstituents blunt the inflammatory cascade in a chemically induced rodent model of hepatocellular carcinogenesis.

Bishayee A, Thoppil RJ, Darvesh AS, Ohanyan V, Meszaros JG, Bhatia D. Bishayee A, et al. Among authors: thoppil rj. J Nutr Biochem. 2013 Jan;24(1):178-87. doi: 10.1016/j.jnutbio.2012.04.009. Epub 2012 Jul 25. J Nutr Biochem. 2013. PMID: 22841394

7

Black currant phytoconstituents exert chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis by suppression of the inflammatory response.

Bishayee A, Thoppil RJ, Mandal A, Darvesh AS, Ohanyan V, Meszaros JG, Háznagy-Radnai E, Hohmann J, Bhatia D. Bishayee A, et al. Among authors: thoppil rj. Mol Carcinog. 2013 Apr;52(4):304-17. doi: 10.1002/mc.21860. Epub 2011 Dec 27. Mol Carcinog. 2013. PMID: 22213170

8

Anthocyanin-rich black currant (Ribes nigrum L.) extract affords chemoprevention against diethylnitrosamine-induced hepatocellular carcinogenesis in rats.

Bishayee A, Mbimba T, Thoppil RJ, Háznagy-Radnai E, Sipos P, Darvesh AS, Folkesson HG, Hohmann J. Bishayee A, et al. Among authors: thoppil rj. J Nutr Biochem. 2011 Nov;22(11):1035-46. doi: 10.1016/j.jnutbio.2010.09.001. Epub 2011 Jan 8. J Nutr Biochem. 2011. PMID: 21216582

9

Pomegranate-mediated chemoprevention of experimental hepatocarcinogenesis involves Nrf2-regulated antioxidant mechanisms.

Bishayee A, Bhatia D, Thoppil RJ, Darvesh AS, Nevo E, Lansky EP. Bishayee A, et al. Among authors: thoppil rj. Carcinogenesis. 2011 Jun;32(6):888-96. doi: 10.1093/carcin/bgr045. Epub 2011 Mar 9. Carcinogenesis. 2011. PMID: 21389260 Free PMC article.

10

Black currant anthocyanins abrogate oxidative stress through Nrf2- mediated antioxidant mechanisms in a rat model of hepatocellular carcinoma.

Thoppil RJ, Bhatia D, Barnes KF, Haznagy-Radnai E, Hohmann J, Darvesh AS, Bishayee A. Thoppil RJ, et al. Curr Cancer Drug Targets. 2012 Nov 1;12(9):1244-57. doi: 10.2174/156800912803987968. Curr Cancer Drug Targets. 2012. PMID: 22873220

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