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Therapeutic applications of spherical nucleic acids.
Barnaby SN, Sita TL, Petrosko SH, Stegh AH, Mirkin CA. Barnaby SN, et al. Among authors: stegh ah. Cancer Treat Res. 2015;166:23-50. doi: 10.1007/978-3-319-16555-4_2. Cancer Treat Res. 2015. PMID: 25895863 Review.
Spherical nucleic acid nanoparticle conjugates as an RNAi-based therapy for glioblastoma.
Jensen SA, Day ES, Ko CH, Hurley LA, Luciano JP, Kouri FM, Merkel TJ, Luthi AJ, Patel PC, Cutler JI, Daniel WL, Scott AW, Rotz MW, Meade TJ, Giljohann DA, Mirkin CA, Stegh AH. Jensen SA, et al. Among authors: stegh ah. Sci Transl Med. 2013 Oct 30;5(209):209ra152. doi: 10.1126/scitranslmed.3006839. Sci Transl Med. 2013. PMID: 24174328 Free PMC article.
Spherical nucleic acids for precision medicine.
Mirkin CA, Stegh AH. Mirkin CA, et al. Among authors: stegh ah. Oncotarget. 2014 Jan 15;5(1):9-10. doi: 10.18632/oncotarget.1757. Oncotarget. 2014. PMID: 24398537 Free PMC article. No abstract available.
miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma.
Kouri FM, Hurley LA, Daniel WL, Day ES, Hua Y, Hao L, Peng CY, Merkel TJ, Queisser MA, Ritner C, Zhang H, James CD, Sznajder JI, Chin L, Giljohann DA, Kessler JA, Peter ME, Mirkin CA, Stegh AH. Kouri FM, et al. Among authors: stegh ah. Genes Dev. 2015 Apr 1;29(7):732-45. doi: 10.1101/gad.257394.114. Genes Dev. 2015. PMID: 25838542 Free PMC article.
Preface.
Mirkin CA, Meade TA, Petrosko SH, Stegh AH. Mirkin CA, et al. Among authors: stegh ah. Cancer Treat Res. 2015;166:v-vii. Cancer Treat Res. 2015. PMID: 26072528 No abstract available.
Ribozyme-Spherical Nucleic Acids.
Rouge JL, Sita TL, Hao L, Kouri FM, Briley WE, Stegh AH, Mirkin CA. Rouge JL, et al. Among authors: stegh ah. J Am Chem Soc. 2015 Aug 26;137(33):10528-10531. doi: 10.1021/jacs.5b07104. Epub 2015 Aug 14. J Am Chem Soc. 2015. PMID: 26271335 Free PMC article.
Dual bioluminescence and near-infrared fluorescence monitoring to evaluate spherical nucleic acid nanoconjugate activity in vivo.
Sita TL, Kouri FM, Hurley LA, Merkel TJ, Chalastanis A, May JL, Ghelfi ST, Cole LE, Cayton TC, Barnaby SN, Sprangers AJ, Savalia N, James CD, Lee A, Mirkin CA, Stegh AH. Sita TL, et al. Among authors: stegh ah. Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4129-4134. doi: 10.1073/pnas.1702736114. Epub 2017 Apr 3. Proc Natl Acad Sci U S A. 2017. PMID: 28373576 Free PMC article.
A first-in-human phase 0 clinical study of RNA interference-based spherical nucleic acids in patients with recurrent glioblastoma.
Kumthekar P, Ko CH, Paunesku T, Dixit K, Sonabend AM, Bloch O, Tate M, Schwartz M, Zuckerman L, Lezon R, Lukas RV, Jovanovic B, McCortney K, Colman H, Chen S, Lai B, Antipova O, Deng J, Li L, Tommasini-Ghelfi S, Hurley LA, Unruh D, Sharma NV, Kandpal M, Kouri FM, Davuluri RV, Brat DJ, Muzzio M, Glass M, Vijayakumar V, Heidel J, Giles FJ, Adams AK, James CD, Woloschak GE, Horbinski C, Stegh AH. Kumthekar P, et al. Among authors: stegh ah. Sci Transl Med. 2021 Mar 10;13(584):eabb3945. doi: 10.1126/scitranslmed.abb3945. Sci Transl Med. 2021. PMID: 33692132 Free PMC article. Clinical Trial.
40 results