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Epigenetic dysregulation and poorer prognosis in DAXX-deficient pancreatic neuroendocrine tumours.
Pipinikas CP, Dibra H, Karpathakis A, Feber A, Novelli M, Oukrif D, Fusai G, Valente R, Caplin M, Meyer T, Teschendorff A, Bell C, Morris TJ, Salomoni P, Luong TV, Davidson B, Beck S, Thirlwell C. Pipinikas CP, et al. Among authors: teschendorff a. Endocr Relat Cancer. 2015 Jun;22(3):L13-8. doi: 10.1530/ERC-15-0108. Epub 2015 Apr 21. Endocr Relat Cancer. 2015. PMID: 25900181 Free PMC article. No abstract available.
An epigenetic signature in peripheral blood predicts active ovarian cancer.
Teschendorff AE, Menon U, Gentry-Maharaj A, Ramus SJ, Gayther SA, Apostolidou S, Jones A, Lechner M, Beck S, Jacobs IJ, Widschwendter M. Teschendorff AE, et al. PLoS One. 2009 Dec 18;4(12):e8274. doi: 10.1371/journal.pone.0008274. PLoS One. 2009. PMID: 20019873 Free PMC article.
Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.
Teschendorff AE, Menon U, Gentry-Maharaj A, Ramus SJ, Weisenberger DJ, Shen H, Campan M, Noushmehr H, Bell CG, Maxwell AP, Savage DA, Mueller-Holzner E, Marth C, Kocjan G, Gayther SA, Jones A, Beck S, Wagner W, Laird PW, Jacobs IJ, Widschwendter M. Teschendorff AE, et al. Genome Res. 2010 Apr;20(4):440-6. doi: 10.1101/gr.103606.109. Epub 2010 Mar 10. Genome Res. 2010. PMID: 20219944 Free PMC article.
Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus.
Bell CG, Finer S, Lindgren CM, Wilson GA, Rakyan VK, Teschendorff AE, Akan P, Stupka E, Down TA, Prokopenko I, Morison IM, Mill J, Pidsley R; International Type 2 Diabetes 1q Consortium; Deloukas P, Frayling TM, Hattersley AT, McCarthy MI, Beck S, Hitman GA. Bell CG, et al. Among authors: teschendorff ae. PLoS One. 2010 Nov 18;5(11):e14040. doi: 10.1371/journal.pone.0014040. PLoS One. 2010. PMID: 21124985 Free PMC article.
Comparative methylome analysis of benign and malignant peripheral nerve sheath tumors.
Feber A, Wilson GA, Zhang L, Presneau N, Idowu B, Down TA, Rakyan VK, Noon LA, Lloyd AC, Stupka E, Schiza V, Teschendorff AE, Schroth GP, Flanagan A, Beck S. Feber A, et al. Among authors: teschendorff ae. Genome Res. 2011 Apr;21(4):515-24. doi: 10.1101/gr.109678.110. Epub 2011 Feb 1. Genome Res. 2011. PMID: 21324880 Free PMC article.
A functional methylome map of ulcerative colitis.
Häsler R, Feng Z, Bäckdahl L, Spehlmann ME, Franke A, Teschendorff A, Rakyan VK, Down TA, Wilson GA, Feber A, Beck S, Schreiber S, Rosenstiel P. Häsler R, et al. Among authors: teschendorff a. Genome Res. 2012 Nov;22(11):2130-7. doi: 10.1101/gr.138347.112. Epub 2012 Jul 23. Genome Res. 2012. PMID: 22826509 Free PMC article.
A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data.
Teschendorff AE, Marabita F, Lechner M, Bartlett T, Tegner J, Gomez-Cabrero D, Beck S. Teschendorff AE, et al. Bioinformatics. 2013 Jan 15;29(2):189-96. doi: 10.1093/bioinformatics/bts680. Epub 2012 Nov 21. Bioinformatics. 2013. PMID: 23175756 Free PMC article.
A key statistical issue is therefore how best to adjust for the two different probe designs. ...AVAILABILITY: BMIQ is freely available from http://code.google.com/p/bmiq/. CONTACT: a.teschendorff@ucl.ac.uk SUPPLEMENTARY INFORMATION: Supplementary data are ava …
A key statistical issue is therefore how best to adjust for the two different probe designs. ...AVAILABILITY: BMIQ is freely availabl …
167 results