Ashkenazi A - Search Results

1

Enhancing the antitumor efficacy of a cell-surface death ligand by covalent membrane display.

Nair PM, Flores H, Gogineni A, Marsters S, Lawrence DA, Kelley RF, Ngu H, Sagolla M, Komuves L, Bourgon R, Settleman J, Ashkenazi A. Nair PM, et al. Among authors: ashkenazi a. Proc Natl Acad Sci U S A. 2015 May 5;112(18):5679-84. doi: 10.1073/pnas.1418962112. Epub 2015 Apr 20. Proc Natl Acad Sci U S A. 2015. PMID: 25902490 Free PMC article.

2

Membrane display and functional analysis of juxtacrine ligand-receptor signaling.

Nair PM, Ngu H, Torres E, Marsters S, Lawrence DA, Stephan JP, Komuves L, Ashkenazi A. Nair PM, et al. Among authors: ashkenazi a. Biotechniques. 2015 Oct 1;59(4):231-8, 240. doi: 10.2144/000114342. eCollection 2015 Oct. Biotechniques. 2015. PMID: 26458551 Free article.

3

Receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution of death receptor (DR) 5 than DR4 to apoptosis signaling.

Kelley RF, Totpal K, Lindstrom SH, Mathieu M, Billeci K, Deforge L, Pai R, Hymowitz SG, Ashkenazi A. Kelley RF, et al. Among authors: ashkenazi a. J Biol Chem. 2005 Jan 21;280(3):2205-12. doi: 10.1074/jbc.M410660200. Epub 2004 Nov 1. J Biol Chem. 2005. PMID: 15520016 Free article.

4

Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis.

Sharp DA, Lawrence DA, Ashkenazi A. Sharp DA, et al. Among authors: ashkenazi a. J Biol Chem. 2005 May 13;280(19):19401-9. doi: 10.1074/jbc.M413962200. Epub 2005 Mar 10. J Biol Chem. 2005. PMID: 15760909 Free article.

5

Death-receptor activation halts clathrin-dependent endocytosis.

Austin CD, Lawrence DA, Peden AA, Varfolomeev EE, Totpal K, De Mazière AM, Klumperman J, Arnott D, Pham V, Scheller RH, Ashkenazi A. Austin CD, et al. Among authors: ashkenazi a. Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10283-10288. doi: 10.1073/pnas.0604044103. Epub 2006 Jun 26. Proc Natl Acad Sci U S A. 2006. PMID: 16801533 Free PMC article.

6

Cooperation of the proapoptotic receptor agonist rhApo2L/TRAIL with the CD20 antibody rituximab against non-Hodgkin lymphoma xenografts.

Daniel D, Yang B, Lawrence DA, Totpal K, Balter I, Lee WP, Gogineni A, Cole MJ, Yee SF, Ross S, Ashkenazi A. Daniel D, et al. Among authors: ashkenazi a. Blood. 2007 Dec 1;110(12):4037-46. doi: 10.1182/blood-2007-02-076075. Epub 2007 Aug 27. Blood. 2007. PMID: 17724141 Free article.

7

Proapoptotic activation of death receptor 5 on tumor endothelial cells disrupts the vasculature and reduces tumor growth.

Wilson NS, Yang A, Yang B, Couto S, Stern H, Gogineni A, Pitti R, Marsters S, Weimer RM, Singh M, Ashkenazi A. Wilson NS, et al. Among authors: ashkenazi a. Cancer Cell. 2012 Jul 10;22(1):80-90. doi: 10.1016/j.ccr.2012.05.014. Cancer Cell. 2012. PMID: 22789540 Free article.

8

E-cadherin couples death receptors to the cytoskeleton to regulate apoptosis.

Lu M, Marsters S, Ye X, Luis E, Gonzalez L, Ashkenazi A. Lu M, et al. Among authors: ashkenazi a. Mol Cell. 2014 Jun 19;54(6):987-998. doi: 10.1016/j.molcel.2014.04.029. Epub 2014 May 29. Mol Cell. 2014. PMID: 24882208 Free article.

9

Apoptosis initiation through the cell-extrinsic pathway.

Nair P, Lu M, Petersen S, Ashkenazi A. Nair P, et al. Among authors: ashkenazi a. Methods Enzymol. 2014;544:99-128. doi: 10.1016/B978-0-12-417158-9.00005-4. Methods Enzymol. 2014. PMID: 24974288

10

Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis.

Lu M, Lawrence DA, Marsters S, Acosta-Alvear D, Kimmig P, Mendez AS, Paton AW, Paton JC, Walter P, Ashkenazi A. Lu M, et al. Among authors: ashkenazi a. Science. 2014 Jul 4;345(6192):98-101. doi: 10.1126/science.1254312. Science. 2014. PMID: 24994655 Free PMC article.

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