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eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression.
Furic L, Rong L, Larsson O, Koumakpayi IH, Yoshida K, Brueschke A, Petroulakis E, Robichaud N, Pollak M, Gaboury LA, Pandolfi PP, Saad F, Sonenberg N. Furic L, et al. Among authors: robichaud n. Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14134-9. doi: 10.1073/pnas.1005320107. Epub 2010 Aug 2. Proc Natl Acad Sci U S A. 2010. PMID: 20679199 Free PMC article.
Translational control in the tumor microenvironment promotes lung metastasis: Phosphorylation of eIF4E in neutrophils.
Robichaud N, Hsu BE, Istomine R, Alvarez F, Blagih J, Ma EH, Morales SV, Dai DL, Li G, Souleimanova M, Guo Q, Del Rincon SV, Miller WH Jr, Ramón Y Cajal S, Park M, Jones RG, Piccirillo CA, Siegel PM, Sonenberg N. Robichaud N, et al. Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2202-E2209. doi: 10.1073/pnas.1717439115. Epub 2018 Feb 20. Proc Natl Acad Sci U S A. 2018. PMID: 29463754 Free PMC article.
Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis.
Zakaria C, Sean P, Hoang HD, Leroux LP, Watson M, Workenhe ST, Hearnden J, Pearl D, Truong VT, Robichaud N, Yanagiya A, Tahmasebi S, Jafarnejad SM, Jia JJ, Pelin A, Diallo JS, Le Boeuf F, Bell JC, Mossman KL, Graber TE, Jaramillo M, Sonenberg N, Alain T. Zakaria C, et al. Among authors: robichaud n. PLoS Pathog. 2018 Aug 23;14(8):e1007264. doi: 10.1371/journal.ppat.1007264. eCollection 2018 Aug. PLoS Pathog. 2018. PMID: 30138450 Free PMC article.
Translational Control in Cancer.
Robichaud N, Sonenberg N, Ruggero D, Schneider RJ. Robichaud N, et al. Cold Spring Harb Perspect Biol. 2019 Jul 1;11(7):a032896. doi: 10.1101/cshperspect.a032896. Cold Spring Harb Perspect Biol. 2019. PMID: 29959193 Free PMC article. Review.
Translational control of the activation of transcription factor NF-κB and production of type I interferon by phosphorylation of the translation factor eIF4E.
Herdy B, Jaramillo M, Svitkin YV, Rosenfeld AB, Kobayashi M, Walsh D, Alain T, Sean P, Robichaud N, Topisirovic I, Furic L, Dowling RJO, Sylvestre A, Rong L, Colina R, Costa-Mattioli M, Fritz JH, Olivier M, Brown E, Mohr I, Sonenberg N. Herdy B, et al. Among authors: robichaud n. Nat Immunol. 2012 Apr 29;13(6):543-550. doi: 10.1038/ni.2291. Nat Immunol. 2012. PMID: 22544393 Free PMC article.
4E-BP-Dependent Translational Control of Irf8 Mediates Adipose Tissue Macrophage Inflammatory Response.
Pearl D, Katsumura S, Amiri M, Tabatabaei N, Zhang X, Vinette V, Pang X, Beug ST, Kim SH, Jones LM, Robichaud N, Ong SG, Jia JJ, Ali H, Tremblay ML, Jaramillo M, Alain T, Morita M, Sonenberg N, Tahmasebi S. Pearl D, et al. Among authors: robichaud n. J Immunol. 2020 May 1;204(9):2392-2400. doi: 10.4049/jimmunol.1900538. Epub 2020 Mar 25. J Immunol. 2020. PMID: 32213561
Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases.
Konicek BW, Stephens JR, McNulty AM, Robichaud N, Peery RB, Dumstorf CA, Dowless MS, Iversen PW, Parsons S, Ellis KE, McCann DJ, Pelletier J, Furic L, Yingling JM, Stancato LF, Sonenberg N, Graff JR. Konicek BW, et al. Among authors: robichaud n. Cancer Res. 2011 Mar 1;71(5):1849-57. doi: 10.1158/0008-5472.CAN-10-3298. Epub 2011 Jan 13. Cancer Res. 2011. PMID: 21233335
22 results