Packer M - Search Results

1

Great Debate: SGLT2 inhibitors should be first-line treatment in heart failure with reduced ejection fraction.

Packer M, Cleland JGF, Bauersachs J. Packer M, et al. Eur Heart J. 2024 May 28:ehae300. doi: 10.1093/eurheartj/ehae300. Online ahead of print. Eur Heart J. 2024. PMID: 38805680 No abstract available.

2

Characterisation of high throughput screening outputs for small molecule degrader discovery.

Bell LE, Bardelle C, Packer MJ, Kastl J, Holdgate GA, Davies G. Bell LE, et al. Among authors: packer mj. SLAS Discov. 2024 May 24:100162. doi: 10.1016/j.slasd.2024.100162. Online ahead of print. SLAS Discov. 2024. PMID: 38797285 Free article.

3

SGLT2 inhibitors act as metabolic transducers to restore healthy nutrient deprivation and surplus signaling in the kidney.

Kume S, Packer M. Kume S, et al. Among authors: packer m. Kidney Int. 2024 Jun;105(6):1172-1176. doi: 10.1016/j.kint.2024.01.044. Kidney Int. 2024. PMID: 38777403 No abstract available.

4

Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations.

Thomson C, Barton P, Braybrooke E, Colclough N, Dong Z, Evans L, Floc'h N, Guérot C, Hargreaves D, Khurana P, Li S, Li X, Lister A, McCoull W, McWilliams L, Orme JP, Packer MJ, Swaih AM, Ward RA, Winlow P, Ye Y. Thomson C, et al. Among authors: packer mj. J Med Chem. 2024 May 21. doi: 10.1021/acs.jmedchem.4c00227. Online ahead of print. J Med Chem. 2024. PMID: 38770784

5

Win Ratio: A Seductive But Potentially Misleading Method for Evaluating Evidence from Clinical Trials.

Butler J, Stockbridge N, Packer M. Butler J, et al. Among authors: packer m. Circulation. 2024 May 14;149(20):1546-1548. doi: 10.1161/CIRCULATIONAHA.123.067786. Epub 2024 May 13. Circulation. 2024. PMID: 38739696 No abstract available.

6

Redefining Iron Deficiency in Patients With Chronic Heart Failure.

Packer M, Anker SD, Butler J, Cleland JGF, Kalra PR, Mentz RJ, Ponikowski P, Talha KM. Packer M, et al. Circulation. 2024 May 11. doi: 10.1161/CIRCULATIONAHA.124.068883. Online ahead of print. Circulation. 2024. PMID: 38733252 Free article. Review. No abstract available.

7

Identification of three mechanistic pathways for iron-deficient heart failure.

Packer M, Anker SD, Butler J, Cleland JGF, Kalra PR, Mentz RJ, Ponikowski P. Packer M, et al. Eur Heart J. 2024 May 11:ehae284. doi: 10.1093/eurheartj/ehae284. Online ahead of print. Eur Heart J. 2024. PMID: 38733250

8

Iron homeostasis, recycling and vulnerability in the stressed kidney: A neglected dimension of iron-deficient heart failure.

Packer M. Packer M. Eur J Heart Fail. 2024 May 10. doi: 10.1002/ejhf.3238. Online ahead of print. Eur J Heart Fail. 2024. PMID: 38727795 Review.

9

Critical re-evaluation of the identification of iron deficiency states and effective iron repletion strategies in patients with chronic heart failure.

Packer M, Anker SD, Butler J, Cleland JGF, Kalra PR, Mentz RJ, Ponikowski P, Talha KM. Packer M, et al. Eur J Heart Fail. 2024 May 10. doi: 10.1002/ejhf.3237. Online ahead of print. Eur J Heart Fail. 2024. PMID: 38727791 Review.

10

SGLT2 Inhibition: Neither a Diuretic nor a Natriuretic.

Packer M. Packer M. J Am Coll Cardiol. 2024 Apr 16;83(15):1399-1402. doi: 10.1016/j.jacc.2024.02.028. J Am Coll Cardiol. 2024. PMID: 38599716 No abstract available.

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