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Malaria. A forward genetic screen identifies erythrocyte CD55 as essential for Plasmodium falciparum invasion.
Egan ES, Jiang RH, Moechtar MA, Barteneva NS, Weekes MP, Nobre LV, Gygi SP, Paulo JA, Frantzreb C, Tani Y, Takahashi J, Watanabe S, Goldberg J, Paul AS, Brugnara C, Root DE, Wiegand RC, Doench JG, Duraisingh MT. Egan ES, et al. Among authors: brugnara c. Science. 2015 May 8;348(6235):711-4. doi: 10.1126/science.aaa3526. Science. 2015. PMID: 25954012 Free PMC article.
Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum.
Egan ES, Weekes MP, Kanjee U, Manzo J, Srinivasan A, Lomas-Francis C, Westhoff C, Takahashi J, Tanaka M, Watanabe S, Brugnara C, Gygi SP, Tani Y, Duraisingh MT. Egan ES, et al. Among authors: brugnara c. Commun Biol. 2018 May 3;1:45. doi: 10.1038/s42003-018-0046-2. eCollection 2018. Commun Biol. 2018. PMID: 30271928 Free PMC article.
Plasmodium vivax infection compromises reticulocyte stability.
Clark MA, Kanjee U, Rangel GW, Chery L, Mascarenhas A, Gomes E, Rathod PK, Brugnara C, Ferreira MU, Duraisingh MT. Clark MA, et al. Among authors: brugnara c. Nat Commun. 2021 Mar 12;12(1):1629. doi: 10.1038/s41467-021-21886-x. Nat Commun. 2021. PMID: 33712609 Free PMC article.
Purinergic signaling is essential for full Psickle activation by hypoxia and by normoxic acid pH in mature human sickle red cells and in vitro-differentiated cultured human sickle reticulocytes.
Vandorpe DH, Rivera A, Ganter M, Dankwa S, Wohlgemuth JG, Dlott JS, Snyder LM, Brugnara C, Duraisingh M, Alper SL. Vandorpe DH, et al. Among authors: brugnara c. Pflugers Arch. 2022 May;474(5):553-565. doi: 10.1007/s00424-022-02665-z. Epub 2022 Feb 16. Pflugers Arch. 2022. PMID: 35169901
Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells.
Giani FC, Fiorini C, Wakabayashi A, Ludwig LS, Salem RM, Jobaliya CD, Regan SN, Ulirsch JC, Liang G, Steinberg-Shemer O, Guo MH, Esko T, Tong W, Brugnara C, Hirschhorn JN, Weiss MJ, Zon LI, Chou ST, French DL, Musunuru K, Sankaran VG. Giani FC, et al. Among authors: brugnara c. Cell Stem Cell. 2016 Jan 7;18(1):73-78. doi: 10.1016/j.stem.2015.09.015. Epub 2015 Oct 22. Cell Stem Cell. 2016. PMID: 26607381 Free PMC article.
288 results