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A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis.
Moriarity BS, Otto GM, Rahrmann EP, Rathe SK, Wolf NK, Weg MT, Manlove LA, LaRue RS, Temiz NA, Molyneux SD, Choi K, Holly KJ, Sarver AL, Scott MC, Forster CL, Modiano JF, Khanna C, Hewitt SM, Khokha R, Yang Y, Gorlick R, Dyer MA, Largaespada DA. Moriarity BS, et al. Among authors: gorlick r. Nat Genet. 2015 Jun;47(6):615-24. doi: 10.1038/ng.3293. Epub 2015 May 11. Nat Genet. 2015. PMID: 25961939 Free PMC article.
Credentialing preclinical pediatric xenograft models using gene expression and tissue microarray analysis.
Whiteford CC, Bilke S, Greer BT, Chen Q, Braunschweig TA, Cenacchi N, Wei JS, Smith MA, Houghton P, Morton C, Reynolds CP, Lock R, Gorlick R, Khanna C, Thiele CJ, Takikita M, Catchpoole D, Hewitt SM, Khan J. Whiteford CC, et al. Among authors: gorlick r. Cancer Res. 2007 Jan 1;67(1):32-40. doi: 10.1158/0008-5472.CAN-06-0610. Cancer Res. 2007. PMID: 17210681
Osteosarcoma.
Gorlick R, Khanna C. Gorlick R, et al. J Bone Miner Res. 2010 Apr;25(4):683-91. doi: 10.1002/jbmr.77. J Bone Miner Res. 2010. PMID: 20205169 Free article.
New targets and approaches in osteosarcoma.
Gill J, Ahluwalia MK, Geller D, Gorlick R. Gill J, et al. Among authors: gorlick r. Pharmacol Ther. 2013 Jan;137(1):89-99. doi: 10.1016/j.pharmthera.2012.09.003. Epub 2012 Sep 14. Pharmacol Ther. 2013. PMID: 22983152 Review.
Genome-wide association study identifies two susceptibility loci for osteosarcoma.
Savage SA, Mirabello L, Wang Z, Gastier-Foster JM, Gorlick R, Khanna C, Flanagan AM, Tirabosco R, Andrulis IL, Wunder JS, Gokgoz N, Patiño-Garcia A, Sierrasesúmaga L, Lecanda F, Kurucu N, Ilhan IE, Sari N, Serra M, Hattinger C, Picci P, Spector LG, Barkauskas DA, Marina N, de Toledo SR, Petrilli AS, Amary MF, Halai D, Thomas DM, Douglass C, Meltzer PS, Jacobs K, Chung CC, Berndt SI, Purdue MP, Caporaso NE, Tucker M, Rothman N, Landi MT, Silverman DT, Kraft P, Hunter DJ, Malats N, Kogevinas M, Wacholder S, Troisi R, Helman L, Fraumeni JF Jr, Yeager M, Hoover RN, Chanock SJ. Savage SA, et al. Among authors: gorlick r. Nat Genet. 2013 Jul;45(7):799-803. doi: 10.1038/ng.2645. Epub 2013 Jun 2. Nat Genet. 2013. PMID: 23727862 Free PMC article.
Toward a drug development path that targets metastatic progression in osteosarcoma.
Khanna C, Fan TM, Gorlick R, Helman LJ, Kleinerman ES, Adamson PC, Houghton PJ, Tap WD, Welch DR, Steeg PS, Merlino G, Sorensen PH, Meltzer P, Kirsch DG, Janeway KA, Weigel B, Randall L, Withrow SJ, Paoloni M, Kaplan R, Teicher BA, Seibel NL, Smith M, Uren A, Patel SR, Trent J, Savage SA, Mirabello L, Reinke D, Barkaukas DA, Krailo M, Bernstein M. Khanna C, et al. Among authors: gorlick r. Clin Cancer Res. 2014 Aug 15;20(16):4200-9. doi: 10.1158/1078-0432.CCR-13-2574. Epub 2014 May 6. Clin Cancer Res. 2014. PMID: 24803583 Free PMC article.
331 results