Garcia KC - Search Results

1

Interleukin-2 activity can be fine tuned with engineered receptor signaling clamps.

Mitra S, Ring AM, Amarnath S, Spangler JB, Li P, Ju W, Fischer S, Oh J, Spolski R, Weiskopf K, Kohrt H, Foley JE, Rajagopalan S, Long EO, Fowler DH, Waldmann TA, Garcia KC, Leonard WJ. Mitra S, et al. Among authors: garcia kc. Immunity. 2015 May 19;42(5):826-38. doi: 10.1016/j.immuni.2015.04.018. Immunity. 2015. PMID: 25992859 Free PMC article.

2

Not just any T cell receptor will do.

Bankovich AJ, Garcia KC. Bankovich AJ, et al. Among authors: garcia kc. Immunity. 2003 Jan;18(1):7-11. doi: 10.1016/s1074-7613(02)00517-4. Immunity. 2003. PMID: 12530971 Free article. Review.

3

Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity.

Maynard J, Petersson K, Wilson DH, Adams EJ, Blondelle SE, Boulanger MJ, Wilson DB, Garcia KC. Maynard J, et al. Among authors: garcia kc. Immunity. 2005 Jan;22(1):81-92. doi: 10.1016/j.immuni.2004.11.015. Immunity. 2005. PMID: 15664161 Free article.

4

Deconstructing the form and function of the TCR/CD3 complex.

Kuhns MS, Davis MM, Garcia KC. Kuhns MS, et al. Among authors: garcia kc. Immunity. 2006 Feb;24(2):133-9. doi: 10.1016/j.immuni.2006.01.006. Immunity. 2006. PMID: 16473826 Free article. Review.

5

Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system.

LaPorte SL, Juo ZS, Vaclavikova J, Colf LA, Qi X, Heller NM, Keegan AD, Garcia KC. LaPorte SL, et al. Among authors: garcia kc. Cell. 2008 Jan 25;132(2):259-72. doi: 10.1016/j.cell.2007.12.030. Cell. 2008. PMID: 18243101 Free PMC article.

6

BacMam system for high-level expression of recombinant soluble and membrane glycoproteins for structural studies.

Dukkipati A, Park HH, Waghray D, Fischer S, Garcia KC. Dukkipati A, et al. Among authors: garcia kc. Protein Expr Purif. 2008 Dec;62(2):160-70. doi: 10.1016/j.pep.2008.08.004. Epub 2008 Aug 22. Protein Expr Purif. 2008. PMID: 18782620 Free PMC article.

7

Structural basis of receptor sharing by interleukin 17 cytokines.

Ely LK, Fischer S, Garcia KC. Ely LK, et al. Among authors: garcia kc. Nat Immunol. 2009 Dec;10(12):1245-51. doi: 10.1038/ni.1813. Epub 2009 Oct 18. Nat Immunol. 2009. PMID: 19838198 Free PMC article.

8

Structural snapshots of full-length Jak1, a transmembrane gp130/IL-6/IL-6Rα cytokine receptor complex, and the receptor-Jak1 holocomplex.

Lupardus PJ, Skiniotis G, Rice AJ, Thomas C, Fischer S, Walz T, Garcia KC. Lupardus PJ, et al. Among authors: garcia kc. Structure. 2011 Jan 12;19(1):45-55. doi: 10.1016/j.str.2010.10.010. Structure. 2011. PMID: 21220115 Free PMC article.

9

T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex.

Adams JJ, Narayanan S, Liu B, Birnbaum ME, Kruse AC, Bowerman NA, Chen W, Levin AM, Connolly JM, Zhu C, Kranz DM, Garcia KC. Adams JJ, et al. Among authors: garcia kc. Immunity. 2011 Nov 23;35(5):681-93. doi: 10.1016/j.immuni.2011.09.013. Immunity. 2011. PMID: 22101157 Free PMC article.

10

Structure of the activating IL-1 receptor signaling complex.

Thomas C, Bazan JF, Garcia KC. Thomas C, et al. Among authors: garcia kc. Nat Struct Mol Biol. 2012 Mar 18;19(4):455-7. doi: 10.1038/nsmb.2260. Nat Struct Mol Biol. 2012. PMID: 22426547 Free PMC article.

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