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FOXA2 rewires AP-1 for transcriptional reprogramming and lineage plasticity in prostate cancer.
Wang Z, Townley SL, Zhang S, Liu M, Li M, Labaf M, Patalano S, Venkataramani K, Siegfried KR, Macoska JA, Han D, Gao S, Risbridger GP, Taylor RA, Lawrence MG, He HH, Selth LA, Cai C. Wang Z, et al. Among authors: siegfried kr. Nat Commun. 2024 Jun 8;15(1):4914. doi: 10.1038/s41467-024-49234-9. Nat Commun. 2024. PMID: 38851846 Free PMC article.
Androgen receptor splice variants drive castration-resistant prostate cancer metastasis by activating distinct transcriptional programs.
Han D, Labaf M, Zhao Y, Owiredu J, Zhang S, Patel K, Venkataramani K, Steinfeld JS, Han W, Li M, Liu M, Wang Z, Besschetnova A, Patalano S, Mulhearn MJ, Macoska JA, Yuan X, Balk SP, Nelson PS, Plymate SR, Gao S, Siegfried KR, Liu R, Stangis MM, Foxa G, Czernik PJ, Williams BO, Zarringhalam K, Li X, Cai C. Han D, et al. Among authors: siegfried kr. J Clin Invest. 2024 Apr 30;134(11):e168649. doi: 10.1172/JCI168649. J Clin Invest. 2024. PMID: 38687617 Free PMC article.
Demethylation of EHMT1/GLP Protein Reprograms Its Transcriptional Activity and Promotes Prostate Cancer Progression.
Besschetnova A, Han W, Liu M, Gao Y, Li M, Wang Z, Labaf M, Patalano S, Venkataramani K, Muriph RE, Macoska JA, Siegfried KR, Evans J, Balk SP, Gao S, Han D, Cai C. Besschetnova A, et al. Among authors: siegfried kr. Cancer Res Commun. 2023 Aug 31;3(8):1716-1730. doi: 10.1158/2767-9764.CRC-23-0208. eCollection 2023 Aug. Cancer Res Commun. 2023. PMID: 37663929 Free PMC article.
SETD7 functions as a transcription repressor in prostate cancer via methylating FOXA1.
Wang Z, Petricca J, Liu M, Zhang S, Chen S, Li M, Besschetnova A, Patalano S, Venkataramani K, Siegfried KR, Macoska JA, Han D, Gao S, Vedadi M, Arrowsmith CH, He HH, Cai C. Wang Z, et al. Among authors: siegfried kr. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2220472120. doi: 10.1073/pnas.2220472120. Epub 2023 Aug 7. Proc Natl Acad Sci U S A. 2023. PMID: 37549269 Free PMC article.
45 results