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Page 1
Direct effects of dexamethasone on human podocytes.
Xing CY, Saleem MA, Coward RJ, Ni L, Witherden IR, Mathieson PW. Xing CY, et al. Among authors: coward rj. Kidney Int. 2006 Sep;70(6):1038-45. doi: 10.1038/sj.ki.5001655. Epub 2006 Jul 12. Kidney Int. 2006. PMID: 16837924 Free article.
Associations among genotype, clinical phenotype, and intracellular localization of trafficking proteins in ARC syndrome.
Smith H, Galmes R, Gogolina E, Straatman-Iwanowska A, Reay K, Banushi B, Bruce CK, Cullinane AR, Romero R, Chang R, Ackermann O, Baumann C, Cangul H, Cakmak Celik F, Aygun C, Coward R, Dionisi-Vici C, Sibbles B, Inward C, Kim CA, Klumperman J, Knisely AS, Watson SP, Gissen P. Smith H, et al. Hum Mutat. 2012 Dec;33(12):1656-64. doi: 10.1002/humu.22155. Epub 2012 Aug 6. Hum Mutat. 2012. PMID: 22753090 Free PMC article.
Insulin directly stimulates VEGF-A production in the glomerular podocyte.
Hale LJ, Hurcombe J, Lay A, Santamaría B, Valverde AM, Saleem MA, Mathieson PW, Welsh GI, Coward RJ. Hale LJ, et al. Among authors: coward rj. Am J Physiol Renal Physiol. 2013 Jul 15;305(2):F182-8. doi: 10.1152/ajprenal.00548.2012. Epub 2013 May 22. Am J Physiol Renal Physiol. 2013. PMID: 23698113 Free PMC article.
Podocyte GSK3 is an evolutionarily conserved critical regulator of kidney function.
Hurcombe JA, Hartley P, Lay AC, Ni L, Bedford JJ, Leader JP, Singh S, Murphy A, Scudamore CL, Marquez E, Barrington AF, Pinto V, Marchetti M, Wong LF, Uney J, Saleem MA, Mathieson PW, Patel S, Walker RJ, Woodgett JR, Quaggin SE, Welsh GI, Coward RJM. Hurcombe JA, et al. Among authors: coward rjm. Nat Commun. 2019 Jan 24;10(1):403. doi: 10.1038/s41467-018-08235-1. Nat Commun. 2019. PMID: 30679422 Free PMC article.
Adeno-associated virus gene therapy prevents progression of kidney disease in genetic models of nephrotic syndrome.
Ding WY, Kuzmuk V, Hunter S, Lay A, Hayes B, Beesley M, Rollason R, Hurcombe JA, Barrington F, Masson C, Cathery W, May C, Tuffin J, Roberts T, Mollet G, Chu CJ, McIntosh J, Coward RJ, Antignac C, Nathwani A, Welsh GI, Saleem MA. Ding WY, et al. Among authors: coward rj. Sci Transl Med. 2023 Aug 9;15(708):eabc8226. doi: 10.1126/scitranslmed.abc8226. Epub 2023 Aug 9. Sci Transl Med. 2023. PMID: 37556557
Shiga toxin targets the podocyte causing hemolytic uremic syndrome through endothelial complement activation.
Bowen EE, Hurcombe JA, Barrington F, Keir LS, Farmer LK, Wherlock MD, Ortiz-Sandoval CG, Bruno V, Bohorquez-Hernandez A, Diatlov D, Rostam-Shirazi N, Wells S, Stewart M, Teboul L, Lay AC, Butler MJ, Pope RJP, Larkai EMS, Morgan BP, Moppett J, Satchell SC, Welsh GI, Walker PD, Licht C, Saleem MA, Coward RJM. Bowen EE, et al. Among authors: coward rjm. Med. 2023 Nov 10;4(11):761-777.e8. doi: 10.1016/j.medj.2023.09.002. Epub 2023 Oct 19. Med. 2023. PMID: 37863058 Free article.
Contrasting consequences of podocyte insulin-like growth factor 1 receptor inhibition.
Hurcombe JA, Barrington F, Marchetti M, Betin VMS, Bowen EE, Lay AC, Ni L, Dayalan L, Pope RJP, Brinkkoetter PT, Holzenberger M, Welsh GI, Coward RJM. Hurcombe JA, et al. Among authors: coward rjm. iScience. 2024 Apr 16;27(5):109749. doi: 10.1016/j.isci.2024.109749. eCollection 2024 May 17. iScience. 2024. PMID: 38706850 Free PMC article.
73 results