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Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.
McElwee JL, Mohanan S, Griffith OL, Breuer HC, Anguish LJ, Cherrington BD, Palmer AM, Howe LR, Subramanian V, Causey CP, Thompson PR, Gray JW, Coonrod SA. McElwee JL, et al. Among authors: subramanian v. BMC Cancer. 2012 Oct 30;12:500. doi: 10.1186/1471-2407-12-500. BMC Cancer. 2012. PMID: 23110523 Free PMC article.
Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation.
Zhang X, Bolt M, Guertin MJ, Chen W, Zhang S, Cherrington BD, Slade DJ, Dreyton CJ, Subramanian V, Bicker KL, Thompson PR, Mancini MA, Lis JT, Coonrod SA. Zhang X, et al. Among authors: subramanian v. Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13331-6. doi: 10.1073/pnas.1203280109. Epub 2012 Aug 1. Proc Natl Acad Sci U S A. 2012. PMID: 22853951 Free PMC article.
Inhibiting protein arginine deiminases has antioxidant consequences.
Witalison EE, Cui X, Hofseth AB, Subramanian V, Causey CP, Thompson PR, Hofseth LJ. Witalison EE, et al. Among authors: subramanian v. J Pharmacol Exp Ther. 2015 Apr;353(1):64-70. doi: 10.1124/jpet.115.222745. Epub 2015 Jan 29. J Pharmacol Exp Ther. 2015. PMID: 25635139 Free PMC article.
Development of a Selective Inhibitor of Protein Arginine Deiminase 2.
Muth A, Subramanian V, Beaumont E, Nagar M, Kerry P, McEwan P, Srinath H, Clancy K, Parelkar S, Thompson PR. Muth A, et al. Among authors: subramanian v. J Med Chem. 2017 Apr 13;60(7):3198-3211. doi: 10.1021/acs.jmedchem.7b00274. Epub 2017 Mar 31. J Med Chem. 2017. PMID: 28328217 Free PMC article.
1,089 results