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The GYF domain protein CD2BP2 is critical for embryogenesis and podocyte function.
Albert GI, Schell C, Kirschner KM, Schäfer S, Naumann R, Müller A, Kretz O, Kuropka B, Girbig M, Hübner N, Krause E, Scholz H, Huber TB, Knobeloch KP, Freund C. Albert GI, et al. Among authors: kretz o. J Mol Cell Biol. 2015 Oct;7(5):402-14. doi: 10.1093/jmcb/mjv039. Epub 2015 Jun 16. J Mol Cell Biol. 2015. PMID: 26082520
Vps34 deficiency reveals the importance of endocytosis for podocyte homeostasis.
Bechtel W, Helmstädter M, Balica J, Hartleben B, Kiefer B, Hrnjic F, Schell C, Kretz O, Liu S, Geist F, Kerjaschki D, Walz G, Huber TB. Bechtel W, et al. Among authors: kretz o. J Am Soc Nephrol. 2013 Apr;24(5):727-43. doi: 10.1681/ASN.2012070700. Epub 2013 Mar 14. J Am Soc Nephrol. 2013. PMID: 23492732 Free PMC article.
Microtubule Associated Protein 1b (MAP1B) Is a Marker of the Microtubular Cytoskeleton in Podocytes but Is Not Essential for the Function of the Kidney Filtration Barrier in Mice.
Gödel M, Temerinac D, Grahammer F, Hartleben B, Kretz O, Riederer BM, Propst F, Kohl S, Huber TB. Gödel M, et al. Among authors: kretz o. PLoS One. 2015 Oct 8;10(10):e0140116. doi: 10.1371/journal.pone.0140116. eCollection 2015. PLoS One. 2015. PMID: 26448484 Free PMC article.
YAP-mediated mechanotransduction determines the podocyte's response to damage.
Rinschen MM, Grahammer F, Hoppe AK, Kohli P, Hagmann H, Kretz O, Bertsch S, Höhne M, Göbel H, Bartram MP, Gandhirajan RK, Krüger M, Brinkkoetter PT, Huber TB, Kann M, Wickström SA, Benzing T, Schermer B. Rinschen MM, et al. Among authors: kretz o. Sci Signal. 2017 Apr 11;10(474):eaaf8165. doi: 10.1126/scisignal.aaf8165. Sci Signal. 2017. PMID: 28400537
The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier.
Schell C, Rogg M, Suhm M, Helmstädter M, Sellung D, Yasuda-Yamahara M, Kretz O, Küttner V, Suleiman H, Kollipara L, Zahedi RP, Sickmann A, Eimer S, Shaw AS, Kramer-Zucker A, Hirano-Kobayashi M, Abe T, Aizawa S, Grahammer F, Hartleben B, Dengjel J, Huber TB. Schell C, et al. Among authors: kretz o. Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):E4621-E4630. doi: 10.1073/pnas.1617004114. Epub 2017 May 23. Proc Natl Acad Sci U S A. 2017. PMID: 28536193 Free PMC article.
151 results