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Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase.
Kliachyna M, Santoni G, Nussbaum V, Renou J, Sanson B, Colletier JP, Arboléas M, Loiodice M, Weik M, Jean L, Renard PY, Nachon F, Baati R. Kliachyna M, et al. Among authors: colletier jp. Eur J Med Chem. 2014 May 6;78:455-67. doi: 10.1016/j.ejmech.2014.03.044. Epub 2014 Mar 15. Eur J Med Chem. 2014. PMID: 24704618
Observing the overall rocking motion of a protein in a crystal.
Ma P, Xue Y, Coquelle N, Haller JD, Yuwen T, Ayala I, Mikhailovskii O, Willbold D, Colletier JP, Skrynnikov NR, Schanda P. Ma P, et al. Among authors: colletier jp. Nat Commun. 2015 Oct 5;6:8361. doi: 10.1038/ncomms9361. Nat Commun. 2015. PMID: 26436197 Free PMC article.
Serial Femtosecond Crystallography and Ultrafast Absorption Spectroscopy of the Photoswitchable Fluorescent Protein IrisFP.
Colletier JP, Sliwa M, Gallat FX, Sugahara M, Guillon V, Schirò G, Coquelle N, Woodhouse J, Roux L, Gotthard G, Royant A, Uriarte LM, Ruckebusch C, Joti Y, Byrdin M, Mizohata E, Nango E, Tanaka T, Tono K, Yabashi M, Adam V, Cammarata M, Schlichting I, Bourgeois D, Weik M. Colletier JP, et al. J Phys Chem Lett. 2016 Mar 3;7(5):882-7. doi: 10.1021/acs.jpclett.5b02789. Epub 2016 Feb 25. J Phys Chem Lett. 2016. PMID: 26866390
De novo phasing with X-ray laser reveals mosquito larvicide BinAB structure.
Colletier JP, Sawaya MR, Gingery M, Rodriguez JA, Cascio D, Brewster AS, Michels-Clark T, Hice RH, Coquelle N, Boutet S, Williams GJ, Messerschmidt M, DePonte DP, Sierra RG, Laksmono H, Koglin JE, Hunter MS, Park HW, Uervirojnangkoorn M, Bideshi DK, Brunger AT, Federici BA, Sauter NK, Eisenberg DS. Colletier JP, et al. Nature. 2016 Nov 3;539(7627):43-47. doi: 10.1038/nature19825. Epub 2016 Sep 28. Nature. 2016. PMID: 27680699 Free PMC article.
82 results