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Mitochonic Acid 5 (MA-5), a Derivative of the Plant Hormone Indole-3-Acetic Acid, Improves Survival of Fibroblasts from Patients with Mitochondrial Diseases.
Suzuki T, Yamaguchi H, Kikusato M, Matsuhashi T, Matsuo A, Sato T, Oba Y, Watanabe S, Minaki D, Saigusa D, Shimbo H, Mori N, Mishima E, Shima H, Akiyama Y, Takeuchi Y, Yuri A, Kikuchi K, Toyohara T, Suzuki C, Kohzuki M, Anzai J, Mano N, Kure S, Yanagisawa T, Tomioka Y, Toyomizu M, Ito S, Osaka H, Hayashi K, Abe T. Suzuki T, et al. Among authors: hayashi k. Tohoku J Exp Med. 2015 Jul;236(3):225-32. doi: 10.1620/tjem.236.225. Tohoku J Exp Med. 2015. PMID: 26118651 Free article.
A novel indole compound MA-35 attenuates renal fibrosis by inhibiting both TNF-α and TGF-β1 pathways.
Shima H, Sasaki K, Suzuki T, Mukawa C, Obara T, Oba Y, Matsuo A, Kobayashi T, Mishima E, Watanabe S, Akiyama Y, Kikuchi K, Matsuhashi T, Oikawa Y, Nanto F, Akiyama Y, Ho HJ, Suzuki C, Saigusa D, Masamune A, Tomioka Y, Masaki T, Ito S, Hayashi KI, Abe T. Shima H, et al. Among authors: hayashi ki. Sci Rep. 2017 May 15;7(1):1884. doi: 10.1038/s41598-017-01702-7. Sci Rep. 2017. PMID: 28507324 Free PMC article.
Mitochonic Acid 5 (MA-5) Facilitates ATP Synthase Oligomerization and Cell Survival in Various Mitochondrial Diseases.
Matsuhashi T, Sato T, Kanno SI, Suzuki T, Matsuo A, Oba Y, Kikusato M, Ogasawara E, Kudo T, Suzuki K, Ohara O, Shimbo H, Nanto F, Yamaguchi H, Saigusa D, Mukaiyama Y, Watabe A, Kikuchi K, Shima H, Mishima E, Akiyama Y, Oikawa Y, Hsin-Jung HO, Akiyama Y, Suzuki C, Uematsu M, Ogata M, Kumagai N, Toyomizu M, Hozawa A, Mano N, Owada Y, Aiba S, Yanagisawa T, Tomioka Y, Kure S, Ito S, Nakada K, Hayashi KI, Osaka H, Abe T. Matsuhashi T, et al. Among authors: hayashi ki. EBioMedicine. 2017 Jun;20:27-38. doi: 10.1016/j.ebiom.2017.05.016. Epub 2017 May 13. EBioMedicine. 2017. PMID: 28579242 Free PMC article.
Mitochondrial dysfunction underlying sporadic inclusion body myositis is ameliorated by the mitochondrial homing drug MA-5.
Oikawa Y, Izumi R, Koide M, Hagiwara Y, Kanzaki M, Suzuki N, Kikuchi K, Matsuhashi T, Akiyama Y, Ichijo M, Watanabe S, Toyohara T, Suzuki T, Mishima E, Akiyama Y, Ogata Y, Suzuki C, Hayashi H, Kodama EN, Hayashi KI, Itoi E, Aoki M, Kure S, Abe T. Oikawa Y, et al. Among authors: hayashi h, hayashi ki. PLoS One. 2020 Dec 2;15(12):e0231064. doi: 10.1371/journal.pone.0231064. eCollection 2020. PLoS One. 2020. PMID: 33264289 Free PMC article.
[111th Scientific Meeting of the Japanese Society of Internal Medicine: Symposium: 2. Perspective of treatment in the vascular lesion of various organs; 5) Biological aspect of chronic kidney disease and the new therapy].
Abe T, Mishima E, Itoh K, Hayashi K. Abe T, et al. Among authors: hayashi k. Nihon Naika Gakkai Zasshi. 2014 Sep 10;103(9):2158-62. doi: 10.2169/naika.103.2158. Nihon Naika Gakkai Zasshi. 2014. PMID: 27522768 Japanese. No abstract available.
Combination therapy with immune checkpoint inhibitors and denosumab improves clinical outcomes in non-small cell lung cancer with bone metastases.
Asano Y, Yamamoto N, Demura S, Hayashi K, Takeuchi A, Kato S, Miwa S, Igarashi K, Higuchi T, Taniguchi Y, Okuda M, Matsumoto I, Yano S, Tsuchiya H. Asano Y, et al. Among authors: hayashi k. Lung Cancer. 2024 Jun 19;193:107858. doi: 10.1016/j.lungcan.2024.107858. Online ahead of print. Lung Cancer. 2024. PMID: 38901176
Forced vital capacity trajectories and risk of lung transplant and ILD-related mortality among patients with rheumatoid arthritis-associated interstitial lung disease.
Venkat RK, Hayashi K, Juge PA, McDermott G, Paudel M, Wang X, Vanni KMM, Kowalski EN, Qian G, Bade KJ, Saavedra AA, Mueller KT, Chang SH, Dellaripa PF, Weinblatt ME, Shadick NA, Doyle TJ, Dieude P, Sparks JA. Venkat RK, et al. Among authors: hayashi k. Clin Rheumatol. 2024 Jun 19. doi: 10.1007/s10067-024-07028-w. Online ahead of print. Clin Rheumatol. 2024. PMID: 38898318
Rheumatoid arthritis and changes on spirometry by smoking status in two prospective longitudinal cohorts.
Hayashi K, McDermott GC, Juge PA, Moll M, Cho MH, Wang X, Paudel ML, Doyle TJ, Kinney GL, Sansone-Poe D, Young K, Dellaripa PF, Wallace ZS, Regan EA, Hunninghake GM, Silverman EK, Ash SY, San Jose Estepar R, Washko GR, Sparks JA. Hayashi K, et al. RMD Open. 2024 Jun 17;10(2):e004281. doi: 10.1136/rmdopen-2024-004281. RMD Open. 2024. PMID: 38886003 Free PMC article.
8,482 results