Chen ZJ - Search Results

1

Molecular basis for the specific recognition of the metazoan cyclic GMP-AMP by the innate immune adaptor protein STING.

Shi H, Wu J, Chen ZJ, Chen C. Shi H, et al. Among authors: chen zj, chen c. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):8947-52. doi: 10.1073/pnas.1507317112. Epub 2015 Jul 6. Proc Natl Acad Sci U S A. 2015. PMID: 26150511 Free PMC article.

2

Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity.

Li XD, Sun L, Seth RB, Pineda G, Chen ZJ. Li XD, et al. Among authors: chen zj. Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17717-22. doi: 10.1073/pnas.0508531102. Epub 2005 Nov 21. Proc Natl Acad Sci U S A. 2005. PMID: 16301520 Free PMC article.

3

Essential role of TAK1 in thymocyte development and activation.

Liu HH, Xie M, Schneider MD, Chen ZJ. Liu HH, et al. Among authors: chen zj. Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11677-82. doi: 10.1073/pnas.0603089103. Epub 2006 Jul 20. Proc Natl Acad Sci U S A. 2006. PMID: 16857737 Free PMC article.

4

MAVS and MyD88 are essential for innate immunity but not cytotoxic T lymphocyte response against respiratory syncytial virus.

Bhoj VG, Sun Q, Bhoj EJ, Somers C, Chen X, Torres JP, Mejias A, Gomez AM, Jafri H, Ramilo O, Chen ZJ. Bhoj VG, et al. Among authors: chen zj, chen x. Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):14046-51. doi: 10.1073/pnas.0804717105. Epub 2008 Sep 9. Proc Natl Acad Sci U S A. 2008. PMID: 18780793 Free PMC article.

5

Endocytic pathway is required for Drosophila Toll innate immune signaling.

Huang HR, Chen ZJ, Kunes S, Chang GD, Maniatis T. Huang HR, et al. Among authors: chen zj. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8322-7. doi: 10.1073/pnas.1004031107. Epub 2010 Apr 19. Proc Natl Acad Sci U S A. 2010. PMID: 20404143 Free PMC article.

6

Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitis.

Li XD, Chiu YH, Ismail AS, Behrendt CL, Wight-Carter M, Hooper LV, Chen ZJ. Li XD, et al. Among authors: chen zj. Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17390-5. doi: 10.1073/pnas.1107114108. Epub 2011 Sep 29. Proc Natl Acad Sci U S A. 2011. PMID: 21960441 Free PMC article.

7

Cyclic di-GMP sensing via the innate immune signaling protein STING.

Yin Q, Tian Y, Kabaleeswaran V, Jiang X, Tu D, Eck MJ, Chen ZJ, Wu H. Yin Q, et al. Among authors: chen zj. Mol Cell. 2012 Jun 29;46(6):735-45. doi: 10.1016/j.molcel.2012.05.029. Epub 2012 Jun 14. Mol Cell. 2012. PMID: 22705373 Free PMC article.

8

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.

Wu J, Sun L, Chen X, Du F, Shi H, Chen C, Chen ZJ. Wu J, et al. Among authors: chen zj, chen c, chen x. Science. 2013 Feb 15;339(6121):826-30. doi: 10.1126/science.1229963. Epub 2012 Dec 20. Science. 2013. PMID: 23258412 Free PMC article.

9

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.

Sun L, Wu J, Du F, Chen X, Chen ZJ. Sun L, et al. Among authors: chen zj, chen x. Science. 2013 Feb 15;339(6121):786-91. doi: 10.1126/science.1232458. Epub 2012 Dec 20. Science. 2013. PMID: 23258413 Free PMC article.

10

Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING.

Zhang X, Shi H, Wu J, Zhang X, Sun L, Chen C, Chen ZJ. Zhang X, et al. Among authors: chen zj, chen c. Mol Cell. 2013 Jul 25;51(2):226-35. doi: 10.1016/j.molcel.2013.05.022. Epub 2013 Jun 6. Mol Cell. 2013. PMID: 23747010 Free PMC article.

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