Machida K - Search Results

1

Oncogenic signaling pathways and origins of tumor-initiating stem-like cells of hepatocellular carcinomas induced by hepatitis C virus, alcohol and/or obesity.

Chen CL, Tsukamoto H, Machida K. Chen CL, et al. Among authors: machida k. Hepatol Int. 2014 Jul;8(3):330-8. doi: 10.1007/s12072-014-9545-5. Epub 2014 Jun 20. Hepatol Int. 2014. PMID: 26202636 Free PMC article.

2

Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog.

Machida K, Tsukamoto H, Mkrtchyan H, Duan L, Dynnyk A, Liu HM, Asahina K, Govindarajan S, Ray R, Ou JH, Seki E, Deshaies R, Miyake K, Lai MM. Machida K, et al. Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1548-53. doi: 10.1073/pnas.0807390106. Epub 2009 Jan 26. Proc Natl Acad Sci U S A. 2009. PMID: 19171902 Free PMC article.

3

"Second hit" models of alcoholic liver disease.

Tsukamoto H, Machida K, Dynnyk A, Mkrtchyan H. Tsukamoto H, et al. Among authors: machida k. Semin Liver Dis. 2009 May;29(2):178-87. doi: 10.1055/s-0029-1214373. Epub 2009 Apr 22. Semin Liver Dis. 2009. PMID: 19387917 Free PMC article. Review.

4

Ethanol augments RANTES/CCL5 expression in rat liver sinusoidal endothelial cells and human endothelial cells via activation of NF-kappa B, HIF-1 alpha, and AP-1.

Yeligar SM, Machida K, Tsukamoto H, Kalra VK. Yeligar SM, et al. Among authors: machida k. J Immunol. 2009 Nov 1;183(9):5964-76. doi: 10.4049/jimmunol.0901564. Epub 2009 Oct 14. J Immunol. 2009. PMID: 19828633 Free PMC article.

5

c-Jun mediates hepatitis C virus hepatocarcinogenesis through signal transducer and activator of transcription 3 and nitric oxide-dependent impairment of oxidative DNA repair.

Machida K, Tsukamoto H, Liu JC, Han YP, Govindarajan S, Lai MM, Akira S, Ou JH. Machida K, et al. Hepatology. 2010 Aug;52(2):480-92. doi: 10.1002/hep.23697. Hepatology. 2010. PMID: 20683948 Free PMC article.

6

Pluripotency factor-mediated expression of the leptin receptor (OB-R) links obesity to oncogenesis through tumor-initiating stem cells.

Feldman DE, Chen C, Punj V, Tsukamoto H, Machida K. Feldman DE, et al. Among authors: machida k. Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):829-34. doi: 10.1073/pnas.1114438109. Epub 2011 Dec 29. Proc Natl Acad Sci U S A. 2012. PMID: 22207628 Free PMC article.

7

Cancer stem cells generated by alcohol, diabetes, and hepatitis C virus.

Machida K, Chen CL, Liu JC, Kashiwabara C, Feldman D, French SW, Sher L, Hyeongnam JJ, Tsukamoto H. Machida K, et al. J Gastroenterol Hepatol. 2012 Mar;27 Suppl 2(Suppl 2):19-22. doi: 10.1111/j.1440-1746.2011.07010.x. J Gastroenterol Hepatol. 2012. PMID: 22320911 Free PMC article. Review.

8

Morphogens and hepatic stellate cell fate regulation in chronic liver disease.

Tsukamoto H, Zhu NL, Wang J, Asahina K, Machida K. Tsukamoto H, et al. Among authors: machida k. J Gastroenterol Hepatol. 2012 Mar;27 Suppl 2(Suppl 2):94-8. doi: 10.1111/j.1440-1746.2011.07022.x. J Gastroenterol Hepatol. 2012. PMID: 22320925 Free PMC article. Review.

9

Mouse intragastric infusion (iG) model.

Ueno A, Lazaro R, Wang PY, Higashiyama R, Machida K, Tsukamoto H. Ueno A, et al. Among authors: machida k. Nat Protoc. 2012 Mar 29;7(4):771-81. doi: 10.1038/nprot.2012.014. Nat Protoc. 2012. PMID: 22461066 Free PMC article.

10

Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitis.

von Montfort C, Matias N, Fernandez A, Fucho R, Conde de la Rosa L, Martinez-Chantar ML, Mato JM, Machida K, Tsukamoto H, Murphy MP, Mansouri A, Kaplowitz N, Garcia-Ruiz C, Fernandez-Checa JC. von Montfort C, et al. Among authors: machida k. J Hepatol. 2012 Oct;57(4):852-9. doi: 10.1016/j.jhep.2012.05.024. Epub 2012 Jun 9. J Hepatol. 2012. PMID: 22687340 Free PMC article.

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