Qin B - Search Results

1

Optimization of N-aryl-6-methoxy-1,2,3,4-tetrahydroquinolines as tubulin polymerization inhibitors.

Wang SB, Wang XF, Qin B, Ohkoshi E, Hsieh KY, Hamel E, Cui MT, Zhu DQ, Goto M, Morris-Natschke SL, Lee KH, Xie L. Wang SB, et al. Among authors: qin b. Bioorg Med Chem. 2015 Sep 1;23(17):5740-7. doi: 10.1016/j.bmc.2015.07.016. Epub 2015 Jul 17. Bioorg Med Chem. 2015. PMID: 26242242 Free PMC article.

2

Discovery of diarylpyridine derivatives as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.

Tian X, Qin B, Lu H, Lai W, Jiang S, Lee KH, Chen CH, Xie L. Tian X, et al. Among authors: qin b. Bioorg Med Chem Lett. 2009 Sep 15;19(18):5482-5. doi: 10.1016/j.bmcl.2009.07.080. Epub 2009 Jul 19. Bioorg Med Chem Lett. 2009. PMID: 19666220 Free PMC article.

3

Diarylaniline derivatives as a distinct class of HIV-1 non-nucleoside reverse transcriptase inhibitors.

Qin B, Jiang X, Lu H, Tian X, Barbault F, Huang L, Qian K, Chen CH, Huang R, Jiang S, Lee KH, Xie L. Qin B, et al. J Med Chem. 2010 Jul 8;53(13):4906-16. doi: 10.1021/jm1002952. J Med Chem. 2010. PMID: 20527972 Free PMC article.

4

Design, synthesis, and evaluation of diarylpyridines and diarylanilines as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.

Tian X, Qin B, Wu Z, Wang X, Lu H, Morris-Natschke SL, Chen CH, Jiang S, Lee KH, Xie L. Tian X, et al. Among authors: qin b. J Med Chem. 2010 Dec 9;53(23):8287-97. doi: 10.1021/jm100738d. Epub 2010 Nov 4. J Med Chem. 2010. PMID: 21049929 Free PMC article.

5

Optimization of 2,4-diarylanilines as non-nucleoside HIV-1 reverse transcriptase inhibitors.

Sun LQ, Qin B, Huang L, Qian K, Chen CH, Lee KH, Xie L. Sun LQ, et al. Among authors: qin b. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2376-9. doi: 10.1016/j.bmcl.2012.02.055. Epub 2012 Feb 24. Bioorg Med Chem Lett. 2012. PMID: 22406117 Free PMC article.

6

Design, synthesis, and preclinical evaluations of novel 4-substituted 1,5-diarylanilines as potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) drug candidates.

Sun LQ, Zhu L, Qian K, Qin B, Huang L, Chen CH, Lee KH, Xie L. Sun LQ, et al. Among authors: qin b. J Med Chem. 2012 Aug 23;55(16):7219-29. doi: 10.1021/jm3007678. Epub 2012 Aug 10. J Med Chem. 2012. PMID: 22856541 Free PMC article.

7

Design and synthesis of diarylamines and diarylethers as cytotoxic antitumor agents.

Wang XF, Tian XT, Ohkoshi E, Qin B, Liu YN, Wu PC, Hour MJ, Hung HY, Qian K, Huang R, Bastow KF, Janzen WP, Jin J, Morris-Natschke SL, Lee KH, Xie L. Wang XF, et al. Among authors: qin b. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6224-8. doi: 10.1016/j.bmcl.2012.08.014. Epub 2012 Aug 9. Bioorg Med Chem Lett. 2012. PMID: 22932313

8

Physicochemical property-driven optimization of diarylaniline compounds as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.

Liu N, Qin B, Sun LQ, Yu F, Lu L, Jiang S, Lee KH, Xie L. Liu N, et al. Among authors: qin b. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3719-23. doi: 10.1016/j.bmcl.2014.07.011. Epub 2014 Jul 11. Bioorg Med Chem Lett. 2014. PMID: 25042339 Free PMC article.

9

Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitor Agents: Optimization of Diarylanilines with High Potency against Wild-Type and Rilpivirine-Resistant E138K Mutant Virus.

Liu N, Wei L, Huang L, Yu F, Zheng W, Qin B, Zhu DQ, Morris-Natschke SL, Jiang S, Chen CH, Lee KH, Xie L. Liu N, et al. Among authors: qin b. J Med Chem. 2016 Apr 28;59(8):3689-704. doi: 10.1021/acs.jmedchem.5b01827. Epub 2016 Apr 12. J Med Chem. 2016. PMID: 27070547 Free PMC article.

10

Optimization of the antiviral potency and lipophilicity of halogenated 2,6-diarylpyridinamines as a novel class of HIV-1 NNRTIS.

Wu ZY, Liu N, Qin B, Huang L, Yu F, Qian K, Morris-Natschke SL, Jiang S, Chen CH, Lee KH, Xie L. Wu ZY, et al. Among authors: qin b. ChemMedChem. 2014 Jul;9(7):1546-55. doi: 10.1002/cmdc.201400075. Epub 2014 Jun 4. ChemMedChem. 2014. PMID: 24895029 Free PMC article.

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