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974 results

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Page 1
Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes.
Cochran RL, Cidado J, Kim M, Zabransky DJ, Croessmann S, Chu D, Wong HY, Beaver JA, Cravero K, Erlanger B, Parsons H, Heaphy CM, Meeker AK, Lauring J, Park BH. Cochran RL, et al. Among authors: park bh. Oncotarget. 2015 Sep 22;6(28):25240-51. doi: 10.18632/oncotarget.4595. Oncotarget. 2015. PMID: 26246475 Free PMC article.
Tamoxifen-stimulated growth of breast cancer due to p21 loss.
Abukhdeir AM, Vitolo MI, Argani P, De Marzo AM, Karakas B, Konishi H, Gustin JP, Lauring J, Garay JP, Pendleton C, Konishi Y, Blair BG, Brenner K, Garrett-Mayer E, Carraway H, Bachman KE, Park BH. Abukhdeir AM, et al. Among authors: park bh. Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):288-93. doi: 10.1073/pnas.0710887105. Epub 2007 Dec 27. Proc Natl Acad Sci U S A. 2008. PMID: 18162533 Free PMC article.
Knockin of mutant PIK3CA activates multiple oncogenic pathways.
Gustin JP, Karakas B, Weiss MB, Abukhdeir AM, Lauring J, Garay JP, Cosgrove D, Tamaki A, Konishi H, Konishi Y, Mohseni M, Wang G, Rosen DM, Denmeade SR, Higgins MJ, Vitolo MI, Bachman KE, Park BH. Gustin JP, et al. Among authors: park bh. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2835-40. doi: 10.1073/pnas.0813351106. Epub 2009 Feb 5. Proc Natl Acad Sci U S A. 2009. PMID: 19196980 Free PMC article.
Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations.
Lauring J, Cosgrove DP, Fontana S, Gustin JP, Konishi H, Abukhdeir AM, Garay JP, Mohseni M, Wang GM, Higgins MJ, Gorkin D, Reis M, Vogelstein B, Polyak K, Cowherd M, Buckhaults PJ, Park BH. Lauring J, et al. Among authors: park bh. Oncogene. 2010 Apr 22;29(16):2337-45. doi: 10.1038/onc.2009.516. Epub 2010 Jan 25. Oncogene. 2010. PMID: 20101210 Free PMC article.
PIK3CA mutations and EGFR overexpression predict for lithium sensitivity in human breast epithelial cells.
Higgins MJ, Beaver JA, Wong HY, Gustin JP, Lauring JD, Garay JP, Konishi H, Mohseni M, Wang GM, Cidado J, Jelovac D, Cosgrove DP, Tamaki A, Abukhdeir AM, Park BH. Higgins MJ, et al. Among authors: park bh. Cancer Biol Ther. 2011 Feb 1;11(3):358-67. doi: 10.4161/cbt.11.3.14227. Epub 2011 Feb 1. Cancer Biol Ther. 2011. PMID: 21124076 Free PMC article.
Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells.
Konishi H, Mohseni M, Tamaki A, Garay JP, Croessmann S, Karnan S, Ota A, Wong HY, Konishi Y, Karakas B, Tahir K, Abukhdeir AM, Gustin JP, Cidado J, Wang GM, Cosgrove D, Cochran R, Jelovac D, Higgins MJ, Arena S, Hawkins L, Lauring J, Gross AL, Heaphy CM, Hosokawa Y, Gabrielson E, Meeker AK, Visvanathan K, Argani P, Bachman KE, Park BH. Konishi H, et al. Among authors: park bh. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17773-8. doi: 10.1073/pnas.1110969108. Epub 2011 Oct 10. Proc Natl Acad Sci U S A. 2011. PMID: 21987798 Free PMC article.
BEAMing sheds light on drug resistance.
Lauring J, Park BH. Lauring J, et al. Among authors: park bh. Clin Cancer Res. 2011 Dec 15;17(24):7508-10. doi: 10.1158/1078-0432.CCR-11-2556. Epub 2011 Nov 7. Clin Cancer Res. 2011. PMID: 22065078 Free PMC article.
974 results