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Efficacy of Berberine in Patients with Non-Alcoholic Fatty Liver Disease.
Yan HM, Xia MF, Wang Y, Chang XX, Yao XZ, Rao SX, Zeng MS, Tu YF, Feng R, Jia WP, Liu J, Deng W, Jiang JD, Gao X. Yan HM, et al. Among authors: gao x. PLoS One. 2015 Aug 7;10(8):e0134172. doi: 10.1371/journal.pone.0134172. eCollection 2015. PLoS One. 2015. PMID: 26252777 Free PMC article. Clinical Trial.
Berberine alleviates nonalcoholic fatty liver induced by a high-fat diet in mice by activating SIRT3.
Xu X, Zhu XP, Bai JY, Xia P, Li Y, Lu Y, Li XY, Gao X. Xu X, et al. Among authors: gao x. FASEB J. 2019 Jun;33(6):7289-7300. doi: 10.1096/fj.201802316R. Epub 2019 Mar 8. FASEB J. 2019. PMID: 30848932
These results suggested that BBR alleviates HFD-induced inhibition of fatty acid beta-OX partly through SIRT3-mediated LCAD deacetylation, which may provide a novel mechanism and support BBR as a promising therapeutic for NAFLD.-Xu, X., Zhu, X.-P., Bai, J.-Y., Xia, …
These results suggested that BBR alleviates HFD-induced inhibition of fatty acid beta-OX partly through SIRT3-mediated LCAD deacetylation, w …
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