McManus KJ - Search Results

1

Targeting SOD1 induces synthetic lethal killing in BLM- and CHEK2-deficient colorectal cancer cells.

Sajesh BV, McManus KJ. Sajesh BV, et al. Among authors: mcmanus kj. Oncotarget. 2015 Sep 29;6(29):27907-22. doi: 10.18632/oncotarget.4875. Oncotarget. 2015. PMID: 26318585 Free PMC article.

2

An evolutionarily conserved synthetic lethal interaction network identifies FEN1 as a broad-spectrum target for anticancer therapeutic development.

van Pel DM, Barrett IJ, Shimizu Y, Sajesh BV, Guppy BJ, Pfeifer T, McManus KJ, Hieter P. van Pel DM, et al. Among authors: mcmanus kj. PLoS Genet. 2013;9(1):e1003254. doi: 10.1371/journal.pgen.1003254. Epub 2013 Jan 31. PLoS Genet. 2013. PMID: 23382697 Free PMC article.

3

Sister chromatid cohesion defects are associated with chromosome instability in Hodgkin lymphoma cells.

Sajesh BV, Lichtensztejn Z, McManus KJ. Sajesh BV, et al. Among authors: mcmanus kj. BMC Cancer. 2013 Aug 20;13:391. doi: 10.1186/1471-2407-13-391. BMC Cancer. 2013. PMID: 23962039 Free PMC article.

4

Synthetic lethal targeting of superoxide dismutase 1 selectively kills RAD54B-deficient colorectal cancer cells.

Sajesh BV, Bailey M, Lichtensztejn Z, Hieter P, McManus KJ. Sajesh BV, et al. Among authors: mcmanus kj. Genetics. 2013 Nov;195(3):757-67. doi: 10.1534/genetics.113.156836. Epub 2013 Sep 3. Genetics. 2013. PMID: 24002644 Free PMC article.

5

Synthetic genetic targeting of genome instability in cancer.

Sajesh BV, Guppy BJ, McManus KJ. Sajesh BV, et al. Among authors: mcmanus kj. Cancers (Basel). 2013 Jun 24;5(3):739-61. doi: 10.3390/cancers5030739. Cancers (Basel). 2013. PMID: 24202319 Free PMC article.

6

The synthetic lethal killing of RAD54B-deficient colorectal cancer cells by PARP1 inhibition is enhanced with SOD1 inhibition.

McAndrew EN, Lepage CC, McManus KJ. McAndrew EN, et al. Among authors: mcmanus kj. Oncotarget. 2016 Dec 27;7(52):87417-87430. doi: 10.18632/oncotarget.13654. Oncotarget. 2016. PMID: 27902462 Free PMC article.

7

Synthetic lethal targeting of RNF20 through PARP1 silencing and inhibition.

Guppy BJ, McManus KJ. Guppy BJ, et al. Among authors: mcmanus kj. Cell Oncol (Dordr). 2017 Jun;40(3):281-292. doi: 10.1007/s13402-017-0323-y. Epub 2017 May 1. Cell Oncol (Dordr). 2017. PMID: 28462496

8

Exploring Candidate Human Synthetic Lethal Interactions Through siRNA and Quantitative Imaging-Based Approaches.

Jeusset LM, McManus KJ. Jeusset LM, et al. Among authors: mcmanus kj. Methods Mol Biol. 2021;2381:151-173. doi: 10.1007/978-1-0716-1740-3_8. Methods Mol Biol. 2021. PMID: 34590275

9

Specific synthetic lethal killing of RAD54B-deficient human colorectal cancer cells by FEN1 silencing.

McManus KJ, Barrett IJ, Nouhi Y, Hieter P. McManus KJ, et al. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3276-81. doi: 10.1073/pnas.0813414106. Epub 2009 Feb 13. Proc Natl Acad Sci U S A. 2009. PMID: 19218431 Free PMC article.

10

Regulation of chromatin structure via histone post-translational modification and the link to carcinogenesis.

Thompson LL, Guppy BJ, Sawchuk L, Davie JR, McManus KJ. Thompson LL, et al. Among authors: mcmanus kj. Cancer Metastasis Rev. 2013 Dec;32(3-4):363-76. doi: 10.1007/s10555-013-9434-8. Cancer Metastasis Rev. 2013. PMID: 23609752 Review.

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