Lopez-Garcia LA - Search Results

1

PI3K/AKT signaling modulates transcriptional expression of EWS/FLI1 through specificity protein 1.

Giorgi C, Boro A, Rechfeld F, Lopez-Garcia LA, Gierisch ME, Schäfer BW, Niggli FK. Giorgi C, et al. Among authors: lopez garcia la. Oncotarget. 2015 Oct 6;6(30):28895-910. doi: 10.18632/oncotarget.5000. Oncotarget. 2015. PMID: 26336820 Free PMC article.

2

Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue.

Gierisch ME, Pfistner F, Lopez-Garcia LA, Harder L, Schäfer BW, Niggli FK. Gierisch ME, et al. Among authors: lopez garcia la. J Biol Chem. 2016 Dec 23;291(52):26922-26933. doi: 10.1074/jbc.M116.752063. Epub 2016 Nov 8. J Biol Chem. 2016. PMID: 27875302 Free PMC article.

3

USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth.

Gierisch ME, Pedot G, Walser F, Lopez-Garcia LA, Jaaks P, Niggli FK, Schäfer BW. Gierisch ME, et al. Among authors: lopez garcia la. Sci Rep. 2019 Jan 30;9(1):951. doi: 10.1038/s41598-018-37264-5. Sci Rep. 2019. PMID: 30700749 Free PMC article.

4

PLK1 phosphorylates PAX3-FOXO1, the inhibition of which triggers regression of alveolar Rhabdomyosarcoma.

Thalhammer V, Lopez-Garcia LA, Herrero-Martin D, Hecker R, Laubscher D, Gierisch ME, Wachtel M, Bode P, Nanni P, Blank B, Koscielniak E, Schäfer BW. Thalhammer V, et al. Among authors: lopez garcia la. Cancer Res. 2015 Jan 1;75(1):98-110. doi: 10.1158/0008-5472.CAN-14-1246. Epub 2014 Nov 14. Cancer Res. 2015. PMID: 25398439 Free article.

5

Regulation of the interaction between protein kinase C-related protein kinase 2 (PRK2) and its upstream kinase, 3-phosphoinositide-dependent protein kinase 1 (PDK1).

Dettori R, Sonzogni S, Meyer L, Lopez-Garcia LA, Morrice NA, Zeuzem S, Engel M, Piiper A, Neimanis S, Frödin M, Biondi RM. Dettori R, et al. J Biol Chem. 2009 Oct 30;284(44):30318-27. doi: 10.1074/jbc.M109.051151. Epub 2009 Sep 1. J Biol Chem. 2009. PMID: 19723632 Free PMC article.

6

Validation of extracellular ligand-receptor interactions by Flow-TriCEPS.

Lopez-Garcia LA, Demiray L, Ruch-Marder S, Hopp AK, Hottiger MO, Helbling PM, Pavlou MP. Lopez-Garcia LA, et al. BMC Res Notes. 2018 Dec 5;11(1):863. doi: 10.1186/s13104-018-3974-5. BMC Res Notes. 2018. PMID: 30518414 Free PMC article.

7

Allosteric activation of the protein kinase PDK1 with low molecular weight compounds.

Engel M, Hindie V, Lopez-Garcia LA, Stroba A, Schaeffer F, Adrian I, Imig J, Idrissova L, Nastainczyk W, Zeuzem S, Alzari PM, Hartmann RW, Piiper A, Biondi RM. Engel M, et al. EMBO J. 2006 Nov 29;25(23):5469-80. doi: 10.1038/sj.emboj.7601416. Epub 2006 Nov 16. EMBO J. 2006. PMID: 17110931 Free PMC article.

8

Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1.

Hindie V, Stroba A, Zhang H, Lopez-Garcia LA, Idrissova L, Zeuzem S, Hirschberg D, Schaeffer F, Jørgensen TJ, Engel M, Alzari PM, Biondi RM. Hindie V, et al. Nat Chem Biol. 2009 Oct;5(10):758-64. doi: 10.1038/nchembio.208. Epub 2009 Aug 30. Nat Chem Biol. 2009. PMID: 19718043

9

Allosteric regulation of protein kinase PKCζ by the N-terminal C1 domain and small compounds to the PIF-pocket.

Lopez-Garcia LA, Schulze JO, Fröhner W, Zhang H, Süss E, Weber N, Navratil J, Amon S, Hindie V, Zeuzem S, Jørgensen TJ, Alzari PM, Neimanis S, Engel M, Biondi RM. Lopez-Garcia LA, et al. Chem Biol. 2011 Nov 23;18(11):1463-73. doi: 10.1016/j.chembiol.2011.08.010. Chem Biol. 2011. PMID: 22118680

10

Use of a fluorescent ATP analog to probe the allosteric conformational change in the active site of the protein kinase PDK1.

Hindie V, Lopez-Garcia LA, Biondi RM. Hindie V, et al. Methods Mol Biol. 2012;928:133-41. doi: 10.1007/978-1-62703-008-3_10. Methods Mol Biol. 2012. PMID: 22956138

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