Lindholm MW - Search Results

1

Altered metabolism of LDL in the arterial wall precedes atherosclerosis regression.

Bartels ED, Christoffersen C, Lindholm MW, Nielsen LB. Bartels ED, et al. Among authors: lindholm mw. Circ Res. 2015 Nov 6;117(11):933-42. doi: 10.1161/CIRCRESAHA.115.307182. Epub 2015 Sep 10. Circ Res. 2015. PMID: 26358193

2

Short locked nucleic acid antisense oligonucleotides potently reduce apolipoprotein B mRNA and serum cholesterol in mice and non-human primates.

Straarup EM, Fisker N, Hedtjärn M, Lindholm MW, Rosenbohm C, Aarup V, Hansen HF, Ørum H, Hansen JB, Koch T. Straarup EM, et al. Among authors: lindholm mw. Nucleic Acids Res. 2010 Nov;38(20):7100-11. doi: 10.1093/nar/gkq457. Epub 2010 Jul 8. Nucleic Acids Res. 2010. PMID: 20615897 Free PMC article.

3

Medial Expression of TNF-α and TNF Receptors Precedes the Development of Atherosclerotic Lesions in Apolipoprotein E/LDL Receptor Double Knockout Mice.

Niemann-Jönsson A, Söderberg I, Lindholm MW, Jovinge S, Nilsson J, Fredrikson GN. Niemann-Jönsson A, et al. Among authors: lindholm mw. Int J Biomed Sci. 2007 Jun;3(2):116-22. Int J Biomed Sci. 2007. PMID: 23675033 Free PMC article.

4

PCSK9 LNA antisense oligonucleotides induce sustained reduction of LDL cholesterol in nonhuman primates.

Lindholm MW, Elmén J, Fisker N, Hansen HF, Persson R, Møller MR, Rosenbohm C, Ørum H, Straarup EM, Koch T. Lindholm MW, et al. Mol Ther. 2012 Feb;20(2):376-81. doi: 10.1038/mt.2011.260. Epub 2011 Nov 22. Mol Ther. 2012. PMID: 22108858 Free PMC article.

5

Antisense-mediated reduction of proprotein convertase subtilisin/kexin type 9 (PCSK9): a first-in-human randomized, placebo-controlled trial.

van Poelgeest EP, Hodges MR, Moerland M, Tessier Y, Levin AA, Persson R, Lindholm MW, Dumong Erichsen K, Ørum H, Cohen AF, Burggraaf J. van Poelgeest EP, et al. Among authors: lindholm mw. Br J Clin Pharmacol. 2015 Dec;80(6):1350-61. doi: 10.1111/bcp.12738. Epub 2015 Oct 24. Br J Clin Pharmacol. 2015. PMID: 26261033 Free PMC article. Clinical Trial.

6

Oats (Avena sativa) reduce atherogenesis in LDL-receptor-deficient mice.

Andersson KE, Svedberg KA, Lindholm MW, Oste R, Hellstrand P. Andersson KE, et al. Among authors: lindholm mw. Atherosclerosis. 2010 Sep;212(1):93-9. doi: 10.1016/j.atherosclerosis.2010.05.001. Epub 2010 May 11. Atherosclerosis. 2010. PMID: 20553794 Free article.

7

DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E.

Lund G, Andersson L, Lauria M, Lindholm M, Fraga MF, Villar-Garea A, Ballestar E, Esteller M, Zaina S. Lund G, et al. J Biol Chem. 2004 Jul 9;279(28):29147-54. doi: 10.1074/jbc.M403618200. Epub 2004 May 6. J Biol Chem. 2004. PMID: 15131116 Free article.

8

Autoimmune responses against the apo B-100 LDL receptor-binding site protect against arterial accumulation of lipids in LDL receptor deficient mice.

Fredrikson GN, Lindholm MW, Ljungcrantz I, Söderberg I, Shah PK, Nilsson J. Fredrikson GN, et al. Among authors: lindholm mw. Autoimmunity. 2007 Mar;40(2):122-30. doi: 10.1080/08916930601165107. Autoimmunity. 2007. PMID: 17453711

9

Silencing of ceramide synthase 2 in hepatocytes modulates plasma ceramide biomarkers predictive of cardiovascular death.

Schmidt S, Gallego SF, Zelnik ID, Kovalchuk S, Albæk N, Sprenger RR, Øverup C, Pewzner-Jung Y, Futerman AH, Lindholm MW, Jensen ON, Ejsing CS. Schmidt S, et al. Among authors: lindholm mw. Mol Ther. 2022 Apr 6;30(4):1661-1674. doi: 10.1016/j.ymthe.2021.08.021. Epub 2021 Aug 14. Mol Ther. 2022. PMID: 34400330 Free PMC article.

10

Perilipin and adipophilin expression in lipid loaded macrophages.

Persson J, Degerman E, Nilsson J, Lindholm MW. Persson J, et al. Among authors: lindholm mw. Biochem Biophys Res Commun. 2007 Nov 30;363(4):1020-6. doi: 10.1016/j.bbrc.2007.09.074. Epub 2007 Sep 29. Biochem Biophys Res Commun. 2007. PMID: 17927964

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