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Neuroprotection by JM-20 against oxygen-glucose deprivation in rat hippocampal slices: Involvement of the Akt/GSK-3β pathway.
Neurochem Int. 2015 Nov;90:215-23. doi: 10.1016/j.neuint.2015.09.003. Epub 2015 Sep 8.
Neurochem Int. 2015.
PMID: 26361722
A novel multi-target ligand (JM-20) protects mitochondrial integrity, inhibits brain excitatory amino acid release and reduces cerebral ischemia injury in vitro and in vivo.
Nuñez-Figueredo Y, Ramírez-Sánchez J, Hansel G, Simões Pires EN, Merino N, Valdes O, Delgado-Hernández R, Parra AL, Ochoa-Rodríguez E, Verdecia-Reyes Y, Salbego C, Costa SL, Souza DO, Pardo-Andreu GL.
Nuñez-Figueredo Y, et al. Among authors: simoes pires en.
Neuropharmacology. 2014 Oct;85:517-27. doi: 10.1016/j.neuropharm.2014.06.009. Epub 2014 Jun 19.
Neuropharmacology. 2014.
PMID: 24953828
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Berberine was neuroprotective against an in vitro model of brain ischemia: survival and apoptosis pathways involved.
Simões Pires EN, Frozza RL, Hoppe JB, Menezes Bde M, Salbego CG.
Simões Pires EN, et al.
Brain Res. 2014 Apr 4;1557:26-33. doi: 10.1016/j.brainres.2014.02.021. Epub 2014 Feb 19.
Brain Res. 2014.
PMID: 24560603
Free article.
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Novel arylidene malonate derivative, KM-34, showed neuroprotective effects on in vitro and in vivo models of ischemia/reperfusion.
Ramírez-Sánchez J, Wong-Guerra M, Fonseca-Fonseca LA, Simões-Pires EN, García-Pupo L, Ochoa-Rodríguez E, Verdecia-Reyes Y, Delgado-Hernández R, Salbego C, Souza DO, Pardo-Andreu GL, Nuñez-Figueredo Y.
Ramírez-Sánchez J, et al. Among authors: simoes pires en.
Eur J Pharmacol. 2021 May 15;899:174025. doi: 10.1016/j.ejphar.2021.174025. Epub 2021 Mar 17.
Eur J Pharmacol. 2021.
PMID: 33722590
Free article.
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Roles of glutamate receptors in a novel in vitro model of early, comorbid cerebrovascular, and Alzheimer's diseases.
Simões-Pires EN, Ferreira ST, Linden R.
Simões-Pires EN, et al.
J Neurochem. 2021 Feb;156(4):539-552. doi: 10.1111/jnc.15129. Epub 2020 Aug 20.
J Neurochem. 2021.
PMID: 32683713
Free article.
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Substrain-related dependence of Cu(I)-ATPase activity among prion protein-null mice.
Adão-Novaes J, Valverde RHF, Landemberger MC, Silveira MS, Simões-Pires EN, Lowe J, Linden R.
Adão-Novaes J, et al. Among authors: simoes pires en.
Brain Res. 2020 Jan 15;1727:146550. doi: 10.1016/j.brainres.2019.146550. Epub 2019 Nov 11.
Brain Res. 2020.
PMID: 31726043
Free article.
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Lecanemab blocks the effects of the Aβ/fibrinogen complex on blood clots and synapse toxicity in organotypic culture.
Singh PK, Simões-Pires EN, Chen ZL, Torrente D, Calvano M, Sharma A, Strickland S, Norris EH.
Singh PK, et al. Among authors: simoes pires en.
Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2314450121. doi: 10.1073/pnas.2314450121. Epub 2024 Apr 15.
Proc Natl Acad Sci U S A. 2024.
PMID: 38621133
Free PMC article.
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