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Yes-associated protein 1 and transcriptional coactivator with PDZ-binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma.
Park YY, Sohn BH, Johnson RL, Kang MH, Kim SB, Shim JJ, Mangala LS, Kim JH, Yoo JE, Rodriguez-Aguayo C, Pradeep S, Hwang JE, Jang HJ, Lee HS, Rupaimoole R, Lopez-Berestein G, Jeong W, Park IS, Park YN, Sood AK, Mills GB, Lee JS. Park YY, et al. Among authors: johnson rl. Hepatology. 2016 Jan;63(1):159-72. doi: 10.1002/hep.28223. Epub 2015 Nov 26. Hepatology. 2016. PMID: 26389641 Free PMC article.
Bile acids activate YAP to promote liver carcinogenesis.
Anakk S, Bhosale M, Schmidt VA, Johnson RL, Finegold MJ, Moore DD. Anakk S, et al. Among authors: johnson rl. Cell Rep. 2013 Nov 27;5(4):1060-9. doi: 10.1016/j.celrep.2013.10.030. Epub 2013 Nov 21. Cell Rep. 2013. PMID: 24268772 Free PMC article.
Hippo coactivator YAP1 upregulates SOX9 and endows esophageal cancer cells with stem-like properties.
Song S, Ajani JA, Honjo S, Maru DM, Chen Q, Scott AW, Heallen TR, Xiao L, Hofstetter WL, Weston B, Lee JH, Wadhwa R, Sudo K, Stroehlein JR, Martin JF, Hung MC, Johnson RL. Song S, et al. Among authors: johnson rl. Cancer Res. 2014 Aug 1;74(15):4170-82. doi: 10.1158/0008-5472.CAN-13-3569. Epub 2014 Jun 6. Cancer Res. 2014. PMID: 24906622 Free PMC article.
Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex.
Liang N, Zhang C, Dill P, Panasyuk G, Pion D, Koka V, Gallazzini M, Olson EN, Lam H, Henske EP, Dong Z, Apte U, Pallet N, Johnson RL, Terzi F, Kwiatkowski DJ, Scoazec JY, Martignoni G, Pende M. Liang N, et al. Among authors: johnson rl. J Exp Med. 2014 Oct 20;211(11):2249-63. doi: 10.1084/jem.20140341. Epub 2014 Oct 6. J Exp Med. 2014. PMID: 25288394 Free PMC article.
1,198 results