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Impaired proinsulin processing is a characteristic of transplanted islets.
Klimek AM, Soukhatcheva G, Thompson DM, Warnock GL, Salehi M, Rilo H, D'Alessio D, Meneilly GS, Panagiotopoulos C, Verchere CB. Klimek AM, et al. Among authors: soukhatcheva g. Am J Transplant. 2009 Sep;9(9):2119-25. doi: 10.1111/j.1600-6143.2009.02740.x. Am J Transplant. 2009. PMID: 19706025 Free article.
Amyloid formation in human islets is enhanced by heparin and inhibited by heparinase.
Potter KJ, Werner I, Denroche HC, Montane J, Plesner A, Chen Y, Lei D, Soukhatcheva G, Warnock GL, Oberholzer J, Fraser PE, Verchere CB. Potter KJ, et al. Among authors: soukhatcheva g. Am J Transplant. 2015 Jun;15(6):1519-30. doi: 10.1111/ajt.13134. Epub 2015 Apr 1. Am J Transplant. 2015. PMID: 25833002 Free article.
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