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Phenotype onset in Huntington's disease knock-in mice is correlated with the incomplete splicing of the mutant huntingtin gene.
J Neurosci Res. 2019 Dec;97(12):1590-1605. doi: 10.1002/jnr.24493. Epub 2019 Jul 7.
J Neurosci Res. 2019.
PMID: 31282030
Free PMC article.
Chronic nicotine improves cognitive and social impairment in mice overexpressing wild type α-synuclein.
Subramaniam SR, Magen I, Bove N, Zhu C, Lemesre V, Dutta G, Elias CJ, Lester HA, Chesselet MF.
Subramaniam SR, et al. Among authors: lemesre v.
Neurobiol Dis. 2018 Sep;117:170-180. doi: 10.1016/j.nbd.2018.05.018. Epub 2018 Jun 1.
Neurobiol Dis. 2018.
PMID: 29859873
Free PMC article.
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MAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomas.
Gruosso T, Garnier C, Abelanet S, Kieffer Y, Lemesre V, Bellanger D, Bieche I, Marangoni E, Sastre-Garau X, Mieulet V, Mechta-Grigoriou F.
Gruosso T, et al. Among authors: lemesre v.
Nat Commun. 2015 Oct 12;6:8583. doi: 10.1038/ncomms9583.
Nat Commun. 2015.
PMID: 26456302
Free PMC article.
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Intranasal NAP (davunetide) decreases tau hyperphosphorylation and moderately improves behavioral deficits in mice overexpressing α-synuclein.
Magen I, Ostritsky R, Richter F, Zhu C, Fleming SM, Lemesre V, Stewart AJ, Morimoto BH, Gozes I, Chesselet MF.
Magen I, et al. Among authors: lemesre v.
Pharmacol Res Perspect. 2014 Oct;2(5):e00065. doi: 10.1002/prp2.65. Epub 2014 Aug 6.
Pharmacol Res Perspect. 2014.
PMID: 25505609
Free PMC article.
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A GCase chaperone improves motor function in a mouse model of synucleinopathy.
Richter F, Fleming SM, Watson M, Lemesre V, Pellegrino L, Ranes B, Zhu C, Mortazavi F, Mulligan CK, Sioshansi PC, Hean S, De La Rosa K, Khanna R, Flanagan J, Lockhart DJ, Wustman BA, Clark SW, Chesselet MF.
Richter F, et al. Among authors: lemesre v.
Neurotherapeutics. 2014 Oct;11(4):840-56. doi: 10.1007/s13311-014-0294-x.
Neurotherapeutics. 2014.
PMID: 25037721
Free PMC article.
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Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons.
Richter F, Gao F, Medvedeva V, Lee P, Bove N, Fleming SM, Michaud M, Lemesre V, Patassini S, De La Rosa K, Mulligan CK, Sioshansi PC, Zhu C, Coppola G, Bordet T, Pruss RM, Chesselet MF.
Richter F, et al. Among authors: lemesre v.
Neurobiol Dis. 2014 Sep;69:263-75. doi: 10.1016/j.nbd.2014.05.012. Epub 2014 May 18.
Neurobiol Dis. 2014.
PMID: 24844147
Free PMC article.
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A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions.
Fleming SM, Mulligan CK, Richter F, Mortazavi F, Lemesre V, Frias C, Zhu C, Stewart A, Gozes I, Morimoto B, Chesselet MF.
Fleming SM, et al. Among authors: lemesre v.
Mol Cell Neurosci. 2011 Mar;46(3):597-606. doi: 10.1016/j.mcn.2010.12.011. Epub 2010 Dec 27.
Mol Cell Neurosci. 2011.
PMID: 21193046
Free PMC article.
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