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Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts.
Cheng KC, Cao S, Raveh A, MacArthur R, Dranchak P, Chlipala G, Okoneski MT, Guha R, Eastman RT, Yuan J, Schultz PJ, Su XZ, Tamayo-Castillo G, Matainaho T, Clardy J, Sherman DH, Inglese J. Cheng KC, et al. Among authors: inglese j. J Nat Prod. 2015 Oct 23;78(10):2411-22. doi: 10.1021/acs.jnatprod.5b00489. Epub 2015 Oct 14. J Nat Prod. 2015. PMID: 26465675 Free PMC article.
Monitoring compound integrity with cytochrome P450 assays and qHTS.
MacArthur R, Leister W, Veith H, Shinn P, Southall N, Austin CP, Inglese J, Auld DS. MacArthur R, et al. Among authors: inglese j. J Biomol Screen. 2009 Jun;14(5):538-46. doi: 10.1177/1087057109336954. Epub 2009 May 29. J Biomol Screen. 2009. PMID: 19483146 Free PMC article.
Identification of pregnane X receptor ligands using time-resolved fluorescence resonance energy transfer and quantitative high-throughput screening.
Shukla SJ, Nguyen DT, Macarthur R, Simeonov A, Frazee WJ, Hallis TM, Marks BD, Singh U, Eliason HC, Printen J, Austin CP, Inglese J, Auld DS. Shukla SJ, et al. Among authors: inglese j. Assay Drug Dev Technol. 2009 Apr;7(2):143-69. doi: 10.1089/adt.2009.193. Assay Drug Dev Technol. 2009. PMID: 19505231 Free PMC article.
Discovery of new antimalarial chemotypes through chemical methodology and library development.
Brown LE, Chih-Chien Cheng K, Wei WG, Yuan P, Dai P, Trilles R, Ni F, Yuan J, MacArthur R, Guha R, Johnson RL, Su XZ, Dominguez MM, Snyder JK, Beeler AB, Schaus SE, Inglese J, Porco JA Jr. Brown LE, et al. Among authors: inglese j. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6775-80. doi: 10.1073/pnas.1017666108. Epub 2011 Apr 15. Proc Natl Acad Sci U S A. 2011. PMID: 21498685 Free PMC article.
198 results