Nitz TJ - Search Results

1

Alkyl Amine Bevirimat Derivatives Are Potent and Broadly Active HIV-1 Maturation Inhibitors.

Urano E, Ablan SD, Mandt R, Pauly GT, Sigano DM, Schneider JP, Martin DE, Nitz TJ, Wild CT, Freed EO. Urano E, et al. Among authors: nitz tj. Antimicrob Agents Chemother. 2015 Oct 19;60(1):190-7. doi: 10.1128/AAC.02121-15. Print 2016 Jan. Antimicrob Agents Chemother. 2015. PMID: 26482309 Free PMC article.

2

Identification of potent maturation inhibitors against HIV-1 clade C.

Timilsina U, Ghimire D, Timalsina B, Nitz TJ, Wild CT, Freed EO, Gaur R. Timilsina U, et al. Among authors: nitz tj. Sci Rep. 2016 Jun 6;6:27403. doi: 10.1038/srep27403. Sci Rep. 2016. PMID: 27264714 Free PMC article.

3

Quenching protein dynamics interferes with HIV capsid maturation.

Wang M, Quinn CM, Perilla JR, Zhang H, Shirra R Jr, Hou G, Byeon IJ, Suiter CL, Ablan S, Urano E, Nitz TJ, Aiken C, Freed EO, Zhang P, Schulten K, Gronenborn AM, Polenova T. Wang M, et al. Among authors: nitz tj. Nat Commun. 2017 Nov 24;8(1):1779. doi: 10.1038/s41467-017-01856-y. Nat Commun. 2017. PMID: 29176596 Free PMC article.

4

Resistance to Second-Generation HIV-1 Maturation Inhibitors.

Urano E, Timilsina U, Kaplan JA, Ablan S, Ghimire D, Pham P, Kuruppu N, Mandt R, Durell SR, Nitz TJ, Martin DE, Wild CT, Gaur R, Freed EO. Urano E, et al. Among authors: nitz tj. J Virol. 2019 Mar 5;93(6):e02017-18. doi: 10.1128/JVI.02017-18. Print 2019 Mar 15. J Virol. 2019. PMID: 30567982 Free PMC article.

5

A single G10T polymorphism in HIV-1 subtype C Gag-SP1 regulates sensitivity to maturation inhibitors.

Ghimire D, Kc Y, Timilsina U, Goel K, Nitz TJ, Wild CT, Gaur R. Ghimire D, et al. Among authors: nitz tj. Retrovirology. 2021 Apr 9;18(1):9. doi: 10.1186/s12977-021-00553-5. Retrovirology. 2021. PMID: 33836787 Free PMC article.

6

The prototype HIV-1 maturation inhibitor, bevirimat, binds to the CA-SP1 cleavage site in immature Gag particles.

Nguyen AT, Feasley CL, Jackson KW, Nitz TJ, Salzwedel K, Air GM, Sakalian M. Nguyen AT, et al. Among authors: nitz tj. Retrovirology. 2011 Dec 7;8:101. doi: 10.1186/1742-4690-8-101. Retrovirology. 2011. PMID: 22151792 Free PMC article.

7

Anti-AIDS agents. 78. Design, synthesis, metabolic stability assessment, and antiviral evaluation of novel betulinic acid derivatives as potent anti-human immunodeficiency virus (HIV) agents.

Qian K, Yu D, Chen CH, Huang L, Morris-Natschke SL, Nitz TJ, Salzwedel K, Reddick M, Allaway GP, Lee KH. Qian K, et al. Among authors: nitz tj. J Med Chem. 2009 May 28;52(10):3248-58. doi: 10.1021/jm900136j. J Med Chem. 2009. PMID: 19388685 Free PMC article.

8

Anti-AIDS agents 73: structure-activity relationship study and asymmetric synthesis of 3-O-monomethylsuccinyl-betulinic acid derivatives.

Qian K, Nakagawa-Goto K, Yu D, Morris-Natschke SL, Nitz TJ, Kilgore N, Allaway GP, Lee KH. Qian K, et al. Among authors: nitz tj. Bioorg Med Chem Lett. 2007 Dec 1;17(23):6553-7. doi: 10.1016/j.bmcl.2007.09.081. Bioorg Med Chem Lett. 2007. PMID: 17935987 Free PMC article.

9

Antipicornavirus activity of tetrazole analogues related to disoxaril.

Diana GD, Cutcliffe D, Volkots DL, Mallamo JP, Bailey TR, Vescio N, Oglesby RC, Nitz TJ, Wetzel J, Giranda V, et al. Diana GD, et al. Among authors: nitz tj. J Med Chem. 1993 Oct 29;36(22):3240-50. doi: 10.1021/jm00074a004. J Med Chem. 1993. PMID: 8230114

10

Picornavirus inhibitors: trifluoromethyl substitution provides a global protective effect against hepatic metabolism.

Diana GD, Rudewicz P, Pevear DC, Nitz TJ, Aldous SC, Aldous DJ, Robinson DT, Draper T, Dutko FJ, Aldi C, et al. Diana GD, et al. Among authors: nitz tj. J Med Chem. 1995 Apr 14;38(8):1355-71. doi: 10.1021/jm00008a014. J Med Chem. 1995. PMID: 7731021

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