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Engagement of the B-cell receptor of chronic lymphocytic leukemia cells drives global and MYC-specific mRNA translation.
Yeomans A, Thirdborough SM, Valle-Argos B, Linley A, Krysov S, Hidalgo MS, Leonard E, Ishfaq M, Wagner SD, Willis AE, Steele AJ, Stevenson FK, Forconi F, Coldwell MJ, Packham G. Yeomans A, et al. Among authors: leonard e. Blood. 2016 Jan 28;127(4):449-57. doi: 10.1182/blood-2015-07-660969. Epub 2015 Oct 21. Blood. 2016. PMID: 26491071 Free article.
PEITC-mediated inhibition of mRNA translation is associated with both inhibition of mTORC1 and increased eIF2α phosphorylation in established cell lines and primary human leukemia cells.
Yeomans A, Lemm E, Wilmore S, Cavell BE, Valle-Argos B, Krysov S, Hidalgo MS, Leonard E, Willis AE, Forconi F, Stevenson FK, Steele AJ, Coldwell MJ, Packham G. Yeomans A, et al. Among authors: leonard e. Oncotarget. 2016 Nov 15;7(46):74807-74819. doi: 10.18632/oncotarget.11655. Oncotarget. 2016. PMID: 27579538 Free PMC article.
Cytokine/Antibody Fusion Protein Design and Evaluation.
Fabilane CS, Stephenson AC, Leonard EK, VanDyke D, Spangler JB. Fabilane CS, et al. Among authors: leonard ek. Curr Protoc. 2024 May;4(5):e1061. doi: 10.1002/cpz1.1061. Curr Protoc. 2024. PMID: 38775006
594 results