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Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes.
Wang ZB, Jiang ZZ, Zhang QH, Hu MW, Huang L, Ou XH, Guo L, Ouyang YC, Hou Y, Brakebusch C, Schatten H, Sun QY. Wang ZB, et al. Mol Biol Cell. 2013 Dec;24(24):3832-41. doi: 10.1091/mbc.E13-03-0123. Epub 2013 Oct 16. Mol Biol Cell. 2013. PMID: 24131996 Free PMC article.
The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading.
Iba K, Albrechtsen R, Gilpin B, Fröhlich C, Loechel F, Zolkiewska A, Ishiguro K, Kojima T, Liu W, Langford JK, Sanderson RD, Brakebusch C, Fässler R, Wewer UM. Iba K, et al. J Cell Biol. 2000 May 29;149(5):1143-56. doi: 10.1083/jcb.149.5.1143. J Cell Biol. 2000. PMID: 10831617 Free PMC article.
RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes.
Jackson B, Peyrollier K, Pedersen E, Basse A, Karlsson R, Wang Z, Lefever T, Ochsenbein AM, Schmidt G, Aktories K, Stanley A, Quondamatteo F, Ladwein M, Rottner K, van Hengel J, Brakebusch C. Jackson B, et al. Mol Biol Cell. 2011 Mar 1;22(5):593-605. doi: 10.1091/mbc.E09-10-0859. Epub 2011 Jan 5. Mol Biol Cell. 2011. PMID: 21209320 Free PMC article.
Rac1 promotes kidney collecting duct integrity by limiting actomyosin activity.
Bock F, Elias BC, Dong X, Parekh DV, Mernaugh G, Viquez OM, Hassan A, Amara VR, Liu J, Brown KL, Terker AS, Chiusa M, Gewin LS, Fogo AB, Brakebusch CH, Pozzi A, Zent R. Bock F, et al. Among authors: brakebusch ch. J Cell Biol. 2021 Nov 1;220(11):e202103080. doi: 10.1083/jcb.202103080. Epub 2021 Oct 14. J Cell Biol. 2021. PMID: 34647970 Free PMC article.
182 results