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Promiscuous RNA binding by Polycomb repressive complex 2.
Davidovich C, Zheng L, Goodrich KJ, Cech TR. Davidovich C, et al. Nat Struct Mol Biol. 2013 Nov;20(11):1250-7. doi: 10.1038/nsmb.2679. Epub 2013 Sep 29. Nat Struct Mol Biol. 2013. PMID: 24077223 Free PMC article.
A dimeric state for PRC2.
Davidovich C, Goodrich KJ, Gooding AR, Cech TR. Davidovich C, et al. Nucleic Acids Res. 2014 Aug;42(14):9236-48. doi: 10.1093/nar/gku540. Epub 2014 Jul 3. Nucleic Acids Res. 2014. PMID: 24992961 Free PMC article.
RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure.
Lu Z, Zhang QC, Lee B, Flynn RA, Smith MA, Robinson JT, Davidovich C, Gooding AR, Goodrich KJ, Mattick JS, Mesirov JP, Cech TR, Chang HY. Lu Z, et al. Among authors: davidovich c. Cell. 2016 May 19;165(5):1267-1279. doi: 10.1016/j.cell.2016.04.028. Epub 2016 May 12. Cell. 2016. PMID: 27180905 Free PMC article.
RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2.
Zhang Q, McKenzie NJ, Warneford-Thomson R, Gail EH, Flanigan SF, Owen BM, Lauman R, Levina V, Garcia BA, Schittenhelm RB, Bonasio R, Davidovich C. Zhang Q, et al. Among authors: davidovich c. Nat Struct Mol Biol. 2019 Mar;26(3):237-247. doi: 10.1038/s41594-019-0197-y. Epub 2019 Mar 4. Nat Struct Mol Biol. 2019. PMID: 30833789 Free PMC article.
Targeting PRC2: RNA offers new opportunities.
Wang X, Davidovich C. Wang X, et al. Among authors: davidovich c. Oncotarget. 2017 Nov 27;8(64):107346-107347. doi: 10.18632/oncotarget.22715. eCollection 2017 Dec 8. Oncotarget. 2017. PMID: 29296169 Free PMC article. No abstract available.
38 results