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The rs2294918 E434K variant modulates patatin-like phospholipase domain-containing 3 expression and liver damage.
Donati B, Motta BM, Pingitore P, Meroni M, Pietrelli A, Alisi A, Petta S, Xing C, Dongiovanni P, del Menico B, Rametta R, Mancina RM, Badiali S, Fracanzani AL, Craxì A, Fargion S, Nobili V, Romeo S, Valenti L. Donati B, et al. Among authors: pingitore p. Hepatology. 2016 Mar;63(3):787-98. doi: 10.1002/hep.28370. Epub 2016 Jan 14. Hepatology. 2016. PMID: 26605757
Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty liver.
Dongiovanni P, Stender S, Pietrelli A, Mancina RM, Cespiati A, Petta S, Pelusi S, Pingitore P, Badiali S, Maggioni M, Mannisto V, Grimaudo S, Pipitone RM, Pihlajamaki J, Craxi A, Taube M, Carlsson LMS, Fargion S, Romeo S, Kozlitina J, Valenti L. Dongiovanni P, et al. Among authors: pingitore p. J Intern Med. 2018 Apr;283(4):356-370. doi: 10.1111/joim.12719. Epub 2017 Dec 27. J Intern Med. 2018. PMID: 29280273 Free PMC article.
DEPDC5 variants increase fibrosis progression in Europeans with chronic hepatitis C virus infection.
Burza MA, Motta BM, Mancina RM, Pingitore P, Pirazzi C, Lepore SM, Spagnuolo R, Doldo P, Russo C, Lazzaro V, Fischer J, Berg T, Aghemo A, Cheroni C, De Francesco R, Fargion S, Colombo M, Datz C, Stickel F, Valenti L, Romeo S. Burza MA, et al. Among authors: pingitore p. Hepatology. 2016 Feb;63(2):418-27. doi: 10.1002/hep.28322. Epub 2015 Dec 18. Hepatology. 2016. PMID: 26517016 Free PMC article.
The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent.
Mancina RM, Dongiovanni P, Petta S, Pingitore P, Meroni M, Rametta R, Borén J, Montalcini T, Pujia A, Wiklund O, Hindy G, Spagnuolo R, Motta BM, Pipitone RM, Craxì A, Fargion S, Nobili V, Käkelä P, Kärjä V, Männistö V, Pihlajamäki J, Reilly DF, Castro-Perez J, Kozlitina J, Valenti L, Romeo S. Mancina RM, et al. Among authors: pingitore p. Gastroenterology. 2016 May;150(5):1219-1230.e6. doi: 10.1053/j.gastro.2016.01.032. Epub 2016 Feb 2. Gastroenterology. 2016. PMID: 26850495 Free PMC article.
The role of PNPLA3 in health and disease.
Pingitore P, Romeo S. Pingitore P, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Jun;1864(6):900-906. doi: 10.1016/j.bbalip.2018.06.018. Epub 2018 Jun 20. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 29935383 Review.
Liver transcriptomics highlights interleukin-32 as novel NAFLD-related cytokine and candidate biomarker.
Baselli GA, Dongiovanni P, Rametta R, Meroni M, Pelusi S, Maggioni M, Badiali S, Pingitore P, Maurotti S, Montalcini T, Taliento AE, Prati D, Rossi G, Fracanzani AL, Mancina RM, Romeo S, Valenti L. Baselli GA, et al. Among authors: pingitore p. Gut. 2020 Oct;69(10):1855-1866. doi: 10.1136/gutjnl-2019-319226. Epub 2020 Jan 30. Gut. 2020. PMID: 32001554 Free PMC article.
PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells.
Pirazzi C, Valenti L, Motta BM, Pingitore P, Hedfalk K, Mancina RM, Burza MA, Indiveri C, Ferro Y, Montalcini T, Maglio C, Dongiovanni P, Fargion S, Rametta R, Pujia A, Andersson L, Ghosal S, Levin M, Wiklund O, Iacovino M, Borén J, Romeo S. Pirazzi C, et al. Among authors: pingitore p. Hum Mol Genet. 2014 Aug 1;23(15):4077-85. doi: 10.1093/hmg/ddu121. Epub 2014 Mar 25. Hum Mol Genet. 2014. PMID: 24670599 Free PMC article.
PNPLA3 148M Carriers with Inflammatory Bowel Diseases Have Higher Susceptibility to Hepatic Steatosis and Higher Liver Enzymes.
Mancina RM, Spagnuolo R, Milano M, Brogneri S, Morrone A, Cosco C, Lazzaro V, Russo C, Ferro Y, Pingitore P, Pujia A, Montalcini T, Doldo P, Garieri P, Piodi L, Caprioli F, Valenti L, Romeo S. Mancina RM, et al. Among authors: pingitore p. Inflamm Bowel Dis. 2016 Jan;22(1):134-40. doi: 10.1097/MIB.0000000000000569. Inflamm Bowel Dis. 2016. PMID: 26355465 Free PMC article.
30 results