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IL-6 down-regulates HLA class II expression and IL-12 production of human dendritic cells to impair activation of antigen-specific CD4(+) T cells.
Ohno Y, Kitamura H, Takahashi N, Ohtake J, Kaneumi S, Sumida K, Homma S, Kawamura H, Minagawa N, Shibasaki S, Taketomi A. Ohno Y, et al. Among authors: kitamura h. Cancer Immunol Immunother. 2016 Feb;65(2):193-204. doi: 10.1007/s00262-015-1791-4. Epub 2016 Jan 12. Cancer Immunol Immunother. 2016. PMID: 26759006 Free PMC article.
The natural killer T (NKT) cell ligand alpha-galactosylceramide demonstrates its immunopotentiating effect by inducing interleukin (IL)-12 production by dendritic cells and IL-12 receptor expression on NKT cells.
Kitamura H, Iwakabe K, Yahata T, Nishimura S, Ohta A, Ohmi Y, Sato M, Takeda K, Okumura K, Van Kaer L, Kawano T, Taniguchi M, Nishimura T. Kitamura H, et al. J Exp Med. 1999 Apr 5;189(7):1121-8. doi: 10.1084/jem.189.7.1121. J Exp Med. 1999. PMID: 10190903 Free PMC article.
The interface between innate and acquired immunity: glycolipid antigen presentation by CD1d-expressing dendritic cells to NKT cells induces the differentiation of antigen-specific cytotoxic T lymphocytes.
Nishimura T, Kitamura H, Iwakabe K, Yahata T, Ohta A, Sato M, Takeda K, Okumura K, Van Kaer L, Kawano T, Taniguchi M, Nakui M, Sekimoto M, Koda T. Nishimura T, et al. Among authors: kitamura h. Int Immunol. 2000 Jul;12(7):987-94. doi: 10.1093/intimm/12.7.987. Int Immunol. 2000. PMID: 10882410
1,783 results