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Synthesis and Pharmacological Evaluation of Novel Adenine-Hydrogen Sulfide Slow Release Hybrids Designed as Multitarget Cardioprotective Agents.
J Med Chem. 2016 Mar 10;59(5):1776-90. doi: 10.1021/acs.jmedchem.5b01223. Epub 2016 Feb 8.
J Med Chem. 2016.
PMID: 26809888
Does perthionitrite (SSNO(-)) account for sustained bioactivity of NO? A (bio)chemical characterization.
Wedmann R, Zahl A, Shubina TE, Dürr M, Heinemann FW, Bugenhagen BE, Burger P, Ivanovic-Burmazovic I, Filipovic MR.
Wedmann R, et al.
Inorg Chem. 2015 Oct 5;54(19):9367-80. doi: 10.1021/acs.inorgchem.5b00831. Epub 2015 Jun 26.
Inorg Chem. 2015.
PMID: 26111441
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Assessment of H2S in vivo using the newly developed mitochondria-targeted mass spectrometry probe MitoA.
Arndt S, Baeza-Garza CD, Logan A, Rosa T, Wedmann R, Prime TA, Martin JL, Saeb-Parsy K, Krieg T, Filipovic MR, Hartley RC, Murphy MP.
Arndt S, et al. Among authors: wedmann r.
J Biol Chem. 2017 May 12;292(19):7761-7773. doi: 10.1074/jbc.M117.784678. Epub 2017 Mar 20.
J Biol Chem. 2017.
PMID: 28320864
Free PMC article.
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Nitrosopersulfide (SSNO-) decomposes in the presence of sulfide, cyanide or glutathione to give HSNO/SNO-: consequences for the assumed role in cell signalling.
Wedmann R, Ivanovic-Burmazovic I, Filipovic MR.
Wedmann R, et al.
Interface Focus. 2017 Apr 6;7(2):20160139. doi: 10.1098/rsfs.2016.0139.
Interface Focus. 2017.
PMID: 28382204
Free PMC article.
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Working with "H2S": facts and apparent artifacts.
Wedmann R, Bertlein S, Macinkovic I, Böltz S, Miljkovic JLj, Muñoz LE, Herrmann M, Filipovic MR.
Wedmann R, et al.
Nitric Oxide. 2014 Sep 15;41:85-96. doi: 10.1016/j.niox.2014.06.003. Epub 2014 Jun 13.
Nitric Oxide. 2014.
PMID: 24932545
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Insights into the mechanism of the reaction between hydrogen sulfide and peroxynitrite.
Cuevasanta E, Zeida A, Carballal S, Wedmann R, Morzan UN, Trujillo M, Radi R, Estrin DA, Filipovic MR, Alvarez B.
Cuevasanta E, et al. Among authors: wedmann r.
Free Radic Biol Med. 2015 Mar;80:93-100. doi: 10.1016/j.freeradbiomed.2014.12.017. Epub 2014 Dec 30.
Free Radic Biol Med. 2015.
PMID: 25555671
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Biosynthesis and Reactivity of Cysteine Persulfides in Signaling.
Yadav PK, Martinov M, Vitvitsky V, Seravalli J, Wedmann R, Filipovic MR, Banerjee R.
Yadav PK, et al. Among authors: wedmann r.
J Am Chem Soc. 2016 Jan 13;138(1):289-99. doi: 10.1021/jacs.5b10494. Epub 2015 Dec 28.
J Am Chem Soc. 2016.
PMID: 26667407
Free PMC article.
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Improved tag-switch method reveals that thioredoxin acts as depersulfidase and controls the intracellular levels of protein persulfidation.
Wedmann R, Onderka C, Wei S, Szijártó IA, Miljkovic JL, Mitrovic A, Lange M, Savitsky S, Yadav PK, Torregrossa R, Harrer EG, Harrer T, Ishii I, Gollasch M, Wood ME, Galardon E, Xian M, Whiteman M, Banerjee R, Filipovic MR.
Wedmann R, et al.
Chem Sci. 2016 May 25;7(5):3414-3426. doi: 10.1039/c5sc04818d. Epub 2016 Feb 19.
Chem Sci. 2016.
PMID: 27170841
Free PMC article.
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