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Combination therapy with renin-angiotensin-aldosterone system inhibitor telmisartan and serine protease inhibitor camostat mesilate provides further renoprotection in a rat chronic kidney disease model.
Narita Y, Ueda M, Uchimura K, Kakizoe Y, Miyasato Y, Mizumoto T, Morinaga J, Hayata M, Nakagawa T, Adachi M, Miyoshi T, Sakai Y, Kadowaki D, Hirata S, Mukoyama M, Kitamura K. Narita Y, et al. Among authors: sakai y. J Pharmacol Sci. 2016 Feb;130(2):110-6. doi: 10.1016/j.jphs.2016.01.003. Epub 2016 Jan 20. J Pharmacol Sci. 2016. PMID: 26887332 Free article.
In vivo contribution of serine proteases to the proteolytic activation of γENaC in aldosterone-infused rats.
Uchimura K, Kakizoe Y, Onoue T, Hayata M, Morinaga J, Yamazoe R, Ueda M, Mizumoto T, Adachi M, Miyoshi T, Shiraishi N, Sakai Y, Tomita K, Kitamura K. Uchimura K, et al. Among authors: sakai y. Am J Physiol Renal Physiol. 2012 Oct;303(7):F939-43. doi: 10.1152/ajprenal.00705.2011. Epub 2012 Jul 25. Am J Physiol Renal Physiol. 2012. PMID: 22832922 Free article.
Effect of a serine protease inhibitor on the progression of chronic renal failure.
Hayata M, Kakizoe Y, Uchimura K, Morinaga J, Yamazoe R, Mizumoto T, Onoue T, Ueda M, Shiraishi N, Adachi M, Miyoshi T, Sakai Y, Tomita K, Kitamura K. Hayata M, et al. Among authors: sakai y. Am J Physiol Renal Physiol. 2012 Oct 15;303(8):F1126-35. doi: 10.1152/ajprenal.00706.2011. Epub 2012 Jul 25. Am J Physiol Renal Physiol. 2012. PMID: 22832926 Free article.
The antifibrotic effect of a serine protease inhibitor in the kidney.
Morinaga J, Kakizoe Y, Miyoshi T, Onoue T, Ueda M, Mizumoto T, Yamazoe R, Uchimura K, Hayata M, Shiraishi N, Adachi M, Sakai Y, Tomita K, Kitamura K. Morinaga J, et al. Among authors: sakai y. Am J Physiol Renal Physiol. 2013 Jul 15;305(2):F173-81. doi: 10.1152/ajprenal.00586.2012. Epub 2013 May 22. Am J Physiol Renal Physiol. 2013. PMID: 23698112 Free article.
A serine protease inhibitor camostat mesilate prevents podocyte apoptosis and attenuates podocyte injury in metabolic syndrome model rats.
Mizumoto T, Kakizoe Y, Nakagawa T, Iwata Y, Miyasato Y, Uchimura K, Adachi M, Deng Q, Hayata M, Morinaga J, Miyoshi T, Izumi Y, Kuwabara T, Sakai Y, Tomita K, Kitamura K, Mukoyama M. Mizumoto T, et al. Among authors: sakai y. J Pharmacol Sci. 2021 Aug;146(4):192-199. doi: 10.1016/j.jphs.2021.04.003. Epub 2021 Apr 24. J Pharmacol Sci. 2021. PMID: 34116732 Free article.
Sustained-release prostacyclin analog ONO-1301 ameliorates tubulointerstitial alterations in a mouse obstructive nephropathy model.
Nasu T, Kinomura M, Tanabe K, Yamasaki H, Htay SL, Saito D, Hinamoto N, Watatani H, Ujike H, Suzuki Y, Sugaya T, Sugiyama H, Sakai Y, Matsumoto K, Maeshima Y, Makino H. Nasu T, et al. Among authors: sakai y. Am J Physiol Renal Physiol. 2012 Jun 15;302(12):F1616-29. doi: 10.1152/ajprenal.00538.2011. Epub 2012 Mar 14. Am J Physiol Renal Physiol. 2012. PMID: 22419696 Free article.
4,505 results