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IL-33 Drives Eosinophil Infiltration and Pathogenic Type 2 Helper T-Cell Immune Responses Leading to Chronic Experimental Ileitis.
De Salvo C, Wang XM, Pastorelli L, Mattioli B, Omenetti S, Buela KA, Chowdhry S, Garg RR, Goodman WA, Rodriguez-Palacios A, Smith DE, Abbott DW, Cominelli F, Bamias G, Xin W, Lee JJ, Vecchi M, Pizarro TT. De Salvo C, et al. Among authors: abbott dw. Am J Pathol. 2016 Apr;186(4):885-98. doi: 10.1016/j.ajpath.2015.11.028. Epub 2016 Feb 22. Am J Pathol. 2016. PMID: 26908008 Free PMC article.
Dysregulated NOD2 predisposes SAMP1/YitFc mice to chronic intestinal inflammation.
Corridoni D, Kodani T, Rodriguez-Palacios A, Pizarro TT, Xin W, Nickerson KP, McDonald C, Ley KF, Abbott DW, Cominelli F. Corridoni D, et al. Among authors: abbott dw. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16999-7004. doi: 10.1073/pnas.1311657110. Epub 2013 Sep 30. Proc Natl Acad Sci U S A. 2013. PMID: 24082103 Free PMC article.
In vivo inhibition of RIPK2 kinase alleviates inflammatory disease.
Tigno-Aranjuez JT, Benderitter P, Rombouts F, Deroose F, Bai X, Mattioli B, Cominelli F, Pizarro TT, Hoflack J, Abbott DW. Tigno-Aranjuez JT, et al. Among authors: abbott dw. J Biol Chem. 2014 Oct 24;289(43):29651-64. doi: 10.1074/jbc.M114.591388. Epub 2014 Sep 11. J Biol Chem. 2014. PMID: 25213858 Free PMC article.
IL-33 promotes recovery from acute colitis by inducing miR-320 to stimulate epithelial restitution and repair.
Lopetuso LR, De Salvo C, Pastorelli L, Rana N, Senkfor HN, Petito V, Di Martino L, Scaldaferri F, Gasbarrini A, Cominelli F, Abbott DW, Goodman WA, Pizarro TT. Lopetuso LR, et al. Among authors: abbott dw. Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9362-E9370. doi: 10.1073/pnas.1803613115. Epub 2018 Sep 17. Proc Natl Acad Sci U S A. 2018. PMID: 30224451 Free PMC article.
GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.
Rana N, Privitera G, Kondolf HC, Bulek K, Lechuga S, De Salvo C, Corridoni D, Antanaviciute A, Maywald RL, Hurtado AM, Zhao J, Huang EH, Li X, Chan ER, Simmons A, Bamias G, Abbott DW, Heaney JD, Ivanov AI, Pizarro TT. Rana N, et al. Among authors: abbott dw. Cell. 2022 Jan 20;185(2):283-298.e17. doi: 10.1016/j.cell.2021.12.024. Epub 2022 Jan 11. Cell. 2022. PMID: 35021065 Free PMC article.
175 results