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Serotonin reciprocally regulates melanocortin neurons to modulate food intake.
Heisler LK, Jobst EE, Sutton GM, Zhou L, Borok E, Thornton-Jones Z, Liu HY, Zigman JM, Balthasar N, Kishi T, Lee CE, Aschkenasi CJ, Zhang CY, Yu J, Boss O, Mountjoy KG, Clifton PG, Lowell BB, Friedman JM, Horvath T, Butler AA, Elmquist JK, Cowley MA. Heisler LK, et al. Neuron. 2006 Jul 20;51(2):239-49. doi: 10.1016/j.neuron.2006.06.004. Neuron. 2006. PMID: 16846858 Free article.
A serotonin and melanocortin circuit mediates D-fenfluramine anorexia.
Xu Y, Jones JE, Lauzon DA, Anderson JG, Balthasar N, Heisler LK, Zinn AR, Lowell BB, Elmquist JK. Xu Y, et al. Among authors: heisler lk. J Neurosci. 2010 Nov 3;30(44):14630-4. doi: 10.1523/JNEUROSCI.5412-09.2010. J Neurosci. 2010. PMID: 21048120 Free PMC article.
Leptin does not directly affect CNS serotonin neurons to influence appetite.
Lam DD, Leinninger GM, Louis GW, Garfield AS, Marston OJ, Leshan RL, Scheller EL, Christensen L, Donato J Jr, Xia J, Evans ML, Elias C, Dalley JW, Burdakov DI, Myers MG Jr, Heisler LK. Lam DD, et al. Among authors: heisler lk. Cell Metab. 2011 May 4;13(5):584-91. doi: 10.1016/j.cmet.2011.03.016. Cell Metab. 2011. PMID: 21531340 Free PMC article.
Melanocortin-3 receptors are involved in adaptation to restricted feeding.
Begriche K, Marston OJ, Rossi J, Burke LK, McDonald P, Heisler LK, Butler AA. Begriche K, et al. Among authors: heisler lk. Genes Brain Behav. 2012 Apr;11(3):291-302. doi: 10.1111/j.1601-183X.2012.00766.x. Epub 2012 Feb 6. Genes Brain Behav. 2012. PMID: 22353545 Free PMC article.
5-HT obesity medication efficacy via POMC activation is maintained during aging.
Burke LK, Doslikova B, D'Agostino G, Garfield AS, Farooq G, Burdakov D, Low MJ, Rubinstein M, Evans ML, Billups B, Heisler LK. Burke LK, et al. Among authors: heisler lk. Endocrinology. 2014 Oct;155(10):3732-8. doi: 10.1210/en.2014-1223. Epub 2014 Jul 22. Endocrinology. 2014. PMID: 25051442 Free PMC article.
Leptin-inhibited PBN neurons enhance responses to hypoglycemia in negative energy balance.
Flak JN, Patterson CM, Garfield AS, D'Agostino G, Goforth PB, Sutton AK, Malec PA, Wong JT, Germani M, Jones JC, Rajala M, Satin L, Rhodes CJ, Olson DP, Kennedy RT, Heisler LK, Myers MG Jr. Flak JN, et al. Among authors: heisler lk. Nat Neurosci. 2014 Dec;17(12):1744-1750. doi: 10.1038/nn.3861. Epub 2014 Nov 10. Nat Neurosci. 2014. PMID: 25383904 Free PMC article.
81 results