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Activation of TRPV2 and BKCa channels by the LL-37 enantiomers stimulates calcium entry and migration of cancer cells.
Oncotarget. 2016 Apr 26;7(17):23785-800. doi: 10.18632/oncotarget.8122.
Oncotarget. 2016.
PMID: 26993604
Free PMC article.
SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline.
Guéguinou M, Harnois T, Crottes D, Uguen A, Deliot N, Gambade A, Chantôme A, Haelters JP, Jaffrès PA, Jourdan ML, Weber G, Soriani O, Bougnoux P, Mignen O, Bourmeyster N, Constantin B, Lecomte T, Vandier C, Potier-Cartereau M.
Guéguinou M, et al. Among authors: gambade a.
Oncotarget. 2016 Jun 14;7(24):36168-36184. doi: 10.18632/oncotarget.8786.
Oncotarget. 2016.
PMID: 27102434
Free PMC article.
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Lipid rafts, KCa/ClCa/Ca2+ channel complexes and EGFR signaling: Novel targets to reduce tumor development by lipids?
Guéguinou M, Gambade A, Félix R, Chantôme A, Fourbon Y, Bougnoux P, Weber G, Potier-Cartereau M, Vandier C.
Guéguinou M, et al. Among authors: gambade a.
Biochim Biophys Acta. 2015 Oct;1848(10 Pt B):2603-20. doi: 10.1016/j.bbamem.2014.10.036. Epub 2014 Nov 4.
Biochim Biophys Acta. 2015.
PMID: 25450343
Free article.
Review.
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Synthetic alkyl-ether-lipid promotes TRPV2 channel trafficking trough PI3K/Akt-girdin axis in cancer cells and increases mammary tumour volume.
Guéguinou M, Felix R, Marionneau-Lambot S, Oullier T, Penna A, Kouba S, Gambade A, Fourbon Y, Ternant D, Arnoult C, Simon G, Bouchet AM, Chantôme A, Harnois T, Haelters JP, Jaffrès PA, Weber G, Bougnoux P, Carreaux F, Mignen O, Vandier C, Potier-Cartereau M.
Guéguinou M, et al. Among authors: gambade a.
Cell Calcium. 2021 Jun 12;97:102435. doi: 10.1016/j.ceca.2021.102435. Online ahead of print.
Cell Calcium. 2021.
PMID: 34167050
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