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Relationship between lung function and quantitative computed tomographic parameters of airway remodeling, air trapping, and emphysema in patients with asthma and chronic obstructive pulmonary disease: A single-center study.
Hartley RA, Barker BL, Newby C, Pakkal M, Baldi S, Kajekar R, Kay R, Laurencin M, Marshall RP, Sousa AR, Parmar H, Siddiqui S, Gupta S, Brightling CE. Hartley RA, et al. Among authors: sousa ar. J Allergy Clin Immunol. 2016 May;137(5):1413-1422.e12. doi: 10.1016/j.jaci.2016.02.001. Epub 2016 Mar 19. J Allergy Clin Immunol. 2016. PMID: 27006248 Free PMC article.
Mepolizumab and exacerbations of refractory eosinophilic asthma.
Haldar P, Brightling CE, Hargadon B, Gupta S, Monteiro W, Sousa A, Marshall RP, Bradding P, Green RH, Wardlaw AJ, Pavord ID. Haldar P, et al. N Engl J Med. 2009 Mar 5;360(10):973-84. doi: 10.1056/NEJMoa0808991. N Engl J Med. 2009. PMID: 19264686 Free PMC article. Clinical Trial.
Mepolizumab, a humanized anti-IL-5 mAb, as a treatment option for severe nasal polyposis.
Gevaert P, Van Bruaene N, Cattaert T, Van Steen K, Van Zele T, Acke F, De Ruyck N, Blomme K, Sousa AR, Marshall RP, Bachert C. Gevaert P, et al. Among authors: sousa ar. J Allergy Clin Immunol. 2011 Nov;128(5):989-95.e1-8. doi: 10.1016/j.jaci.2011.07.056. Epub 2011 Sep 28. J Allergy Clin Immunol. 2011. PMID: 21958585 Free article. Clinical Trial.
Elevated sputum interleukin-5 and submucosal eosinophilia in obese individuals with severe asthma.
Desai D, Newby C, Symon FA, Haldar P, Shah S, Gupta S, Bafadhel M, Singapuri A, Siddiqui S, Woods J, Herath A, Anderson IK, Bradding P, Green R, Kulkarni N, Pavord I, Marshall RP, Sousa AR, May RD, Wardlaw AJ, Brightling CE. Desai D, et al. Among authors: sousa ar. Am J Respir Crit Care Med. 2013 Sep 15;188(6):657-63. doi: 10.1164/rccm.201208-1470OC. Am J Respir Crit Care Med. 2013. PMID: 23590263 Free PMC article.
Quantitative computed tomography-derived clusters: redefining airway remodeling in asthmatic patients.
Gupta S, Hartley R, Khan UT, Singapuri A, Hargadon B, Monteiro W, Pavord ID, Sousa AR, Marshall RP, Subramanian D, Parr D, Entwisle JJ, Siddiqui S, Raj V, Brightling CE. Gupta S, et al. Among authors: sousa ar. J Allergy Clin Immunol. 2014 Mar;133(3):729-38.e18. doi: 10.1016/j.jaci.2013.09.039. Epub 2013 Nov 12. J Allergy Clin Immunol. 2014. PMID: 24238646 Free PMC article.
Temporal assessment of airway remodeling in severe asthma using quantitative computed tomography.
Gupta S, Hartley R, Singapuri A, Hargadon B, Monteiro W, Pavord ID, Sousa AR, Marshall RP, Subramanian D, Parr D, Entwisle JJ, Siddiqui S, Raj V, Brightling CE. Gupta S, et al. Among authors: sousa ar. Am J Respir Crit Care Med. 2015 Jan 1;191(1):107-10. doi: 10.1164/rccm.201406-1128LE. Am J Respir Crit Care Med. 2015. PMID: 25551349 Free PMC article. No abstract available.
U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics.
Lefaudeux D, De Meulder B, Loza MJ, Peffer N, Rowe A, Baribaud F, Bansal AT, Lutter R, Sousa AR, Corfield J, Pandis I, Bakke PS, Caruso M, Chanez P, Dahlén SE, Fleming LJ, Fowler SJ, Horvath I, Krug N, Montuschi P, Sanak M, Sandstrom T, Shaw DE, Singer F, Sterk PJ, Roberts G, Adcock IM, Djukanovic R, Auffray C, Chung KF; U-BIOPRED Study Group. Lefaudeux D, et al. Among authors: sousa ar. J Allergy Clin Immunol. 2017 Jun;139(6):1797-1807. doi: 10.1016/j.jaci.2016.08.048. Epub 2016 Oct 20. J Allergy Clin Immunol. 2017. PMID: 27773852 Free article.
Assessment of the efficacy and safety of fluticasone propionate and salmeterol delivered as a combination dry powder via a capsule-based inhaler versus a multi-dose inhaler in patients with chronic obstructive pulmonary disease.
Chan R, Sousa AR, Hynds P, Homayoun-Valiani F, Edwards D, Tabberer M. Chan R, et al. Among authors: sousa ar. Pulm Pharmacol Ther. 2017 Apr;43:12-19. doi: 10.1016/j.pupt.2017.01.009. Epub 2017 Jan 21. Pulm Pharmacol Ther. 2017. PMID: 28115223 Clinical Trial.
Severe asthma: Differential chemokine response of airway epithelial cells.
Thomas B, Hirst RA, Brett-Pitt MH, Williams G, Andrew PW, Sousa AR, Marshall RP, Brightling C, O'Callaghan C. Thomas B, et al. Among authors: sousa ar. J Allergy Clin Immunol. 2017 Oct;140(4):1149-1152.e10. doi: 10.1016/j.jaci.2017.02.040. Epub 2017 Apr 12. J Allergy Clin Immunol. 2017. PMID: 28412395 No abstract available.
Associations in asthma between quantitative computed tomography and bronchial biopsy-derived airway remodelling.
Berair R, Hartley R, Mistry V, Sheshadri A, Gupta S, Singapuri A, Gonem S, Marshall RP, Sousa AR, Shikotra A, Kay R, Wardlaw A, Bradding P, Siddiqui S, Castro M, Brightling CE. Berair R, et al. Among authors: sousa ar. Eur Respir J. 2017 May 1;49(5):1601507. doi: 10.1183/13993003.01507-2016. Print 2017 May. Eur Respir J. 2017. PMID: 28461289 Free PMC article.
225 results