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Synthesis, bioevaluation and docking study of 5-substitutedphenyl-1,3,4-thiadiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents.
Nam NH, Huong TL, Dung do TM, Dung PT, Oanh DT, Park SH, Kim K, Han BW, Yun J, Kang JS, Kim Y, Han SB. Nam NH, et al. Among authors: han bw, han sb. J Enzyme Inhib Med Chem. 2014 Oct;29(5):611-8. doi: 10.3109/14756366.2013.832238. Epub 2013 Sep 11. J Enzyme Inhib Med Chem. 2014. PMID: 24020585
Novel HDAC inhibitor MAKV-8 and imatinib synergistically kill chronic myeloid leukemia cells via inhibition of BCR-ABL/MYC-signaling: effect on imatinib resistance and stem cells.
Lernoux M, Schnekenburger M, Losson H, Vermeulen K, Hahn H, Gérard D, Lee JY, Mazumder A, Ahamed M, Christov C, Kim DW, Dicato M, Bormans G, Han BW, Diederich M. Lernoux M, et al. Among authors: han bw. Clin Epigenetics. 2020 May 19;12(1):69. doi: 10.1186/s13148-020-00839-z. Clin Epigenetics. 2020. PMID: 32430012 Free PMC article.
152 results