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Soluble guanylate cyclase as an alternative target for bronchodilator therapy in asthma.
Ghosh A, Koziol-White CJ, Asosingh K, Cheng G, Ruple L, Groneberg D, Friebe A, Comhair SA, Stasch JP, Panettieri RA Jr, Aronica MA, Erzurum SC, Stuehr DJ. Ghosh A, et al. Among authors: asosingh k. Proc Natl Acad Sci U S A. 2016 Apr 26;113(17):E2355-62. doi: 10.1073/pnas.1524398113. Epub 2016 Apr 11. Proc Natl Acad Sci U S A. 2016. PMID: 27071111 Free PMC article.
An inherent dysfunction in soluble guanylyl cyclase is present in the airway of severe asthmatics and is associated with aberrant redox enzyme expression and compromised NO-cGMP signaling.
Ghosh A, Koziol-White CJ, Jester WF Jr, Erzurum SC, Asosingh K, Panettieri RA Jr, Stuehr DJ. Ghosh A, et al. Among authors: asosingh k. Redox Biol. 2021 Feb;39:101832. doi: 10.1016/j.redox.2020.101832. Epub 2020 Dec 13. Redox Biol. 2021. PMID: 33360351 Free PMC article.
Nascent endothelium initiates Th2 polarization of asthma.
Asosingh K, Cheng G, Xu W, Savasky BM, Aronica MA, Li X, Erzurum SC. Asosingh K, et al. J Immunol. 2013 Apr 1;190(7):3458-65. doi: 10.4049/jimmunol.1202095. Epub 2013 Feb 20. J Immunol. 2013. PMID: 23427249 Free PMC article.
Redox imaging of inflammation in asthma.
Ratanamaneechat S, Neumann DR, Difilippo FP, Comhair SA, Asosingh K, Ghosh S, Grandon D, Khan A, Aronica MA, Erzurum SC. Ratanamaneechat S, et al. Among authors: asosingh k. Am J Respir Crit Care Med. 2014 Mar 15;189(6):743-6. doi: 10.1164/rccm.201310-1872LE. Am J Respir Crit Care Med. 2014. PMID: 24628314 Free PMC article. No abstract available.
Angioplasticity in asthma.
Asosingh K, Erzurum SC. Asosingh K, et al. Biochem Soc Trans. 2009 Aug;37(Pt 4):805-10. doi: 10.1042/BST0370805. Biochem Soc Trans. 2009. PMID: 19614598 Free PMC article. Review.
117 results