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Wnt/β-catenin signaling plays an ever-expanding role in stem cell self-renewal, tumorigenesis and cancer chemoresistance.
Mohammed MK, Shao C, Wang J, Wei Q, Wang X, Collier Z, Tang S, Liu H, Zhang F, Huang J, Guo D, Lu M, Liu F, Liu J, Ma C, Shi LL, Athiviraham A, He TC, Lee MJ. Mohammed MK, et al. Among authors: ma c. Genes Dis. 2016 Mar;3(1):11-40. doi: 10.1016/j.gendis.2015.12.004. Epub 2016 Jan 14. Genes Dis. 2016. PMID: 27077077 Free PMC article.
Transition to resistance: An unexpected role of the EMT in cancer chemoresistance.
Wang J, Wei Q, Wang X, Tang S, Liu H, Zhang F, Mohammed MK, Huang J, Guo D, Lu M, Liu F, Liu J, Ma C, Hu X, Haydon RC, He TC, Luu HH. Wang J, et al. Among authors: ma c. Genes Dis. 2016 Mar;3(1):3-6. doi: 10.1016/j.gendis.2016.01.002. Epub 2016 Jan 28. Genes Dis. 2016. PMID: 28491932 Free PMC article.
Anthelmintic mebendazole enhances cisplatin's effect on suppressing cell proliferation and promotes differentiation of head and neck squamous cell carcinoma (HNSCC).
Zhang F, Li Y, Zhang H, Huang E, Gao L, Luo W, Wei Q, Fan J, Song D, Liao J, Zou Y, Liu F, Liu J, Huang J, Guo D, Ma C, Hu X, Li L, Qu X, Chen L, Yu X, Zhang Z, Wu T, Luu HH, Haydon RC, Song J, He TC, Ji P. Zhang F, et al. Among authors: ma c. Oncotarget. 2017 Feb 21;8(8):12968-12982. doi: 10.18632/oncotarget.14673. Oncotarget. 2017. PMID: 28099902 Free PMC article.
Noncanonical Wnt signaling plays an important role in modulating canonical Wnt-regulated stemness, proliferation and terminal differentiation of hepatic progenitors.
Fan J, Wei Q, Liao J, Zou Y, Song D, Xiong D, Ma C, Hu X, Qu X, Chen L, Li L, Yu Y, Yu X, Zhang Z, Zhao C, Zeng Z, Zhang R, Yan S, Wu T, Wu X, Shu Y, Lei J, Li Y, Zhang W, Haydon RC, Luu HH, Huang A, He TC, Tang H. Fan J, et al. Among authors: ma c. Oncotarget. 2017 Apr 18;8(16):27105-27119. doi: 10.18632/oncotarget.15637. Oncotarget. 2017. PMID: 28404920 Free PMC article.
A thermoresponsive polydiolcitrate-gelatin scaffold and delivery system mediates effective bone formation from BMP9-transduced mesenchymal stem cells.
Ye J, Wang J, Zhu Y, Wei Q, Wang X, Yang J, Tang S, Liu H, Fan J, Zhang F, Farina EM, Mohammed MK, Zou Y, Song D, Liao J, Huang J, Guo D, Lu M, Liu F, Liu J, Li L, Ma C, Hu X, Haydon RC, Lee MJ, Reid RR, Ameer GA, Yang L, He TC. Ye J, et al. Among authors: ma c. Biomed Mater. 2016 Apr 21;11(2):025021. doi: 10.1088/1748-6041/11/2/025021. Biomed Mater. 2016. PMID: 27097687
Bone morphogenetic protein 9 (BMP9) induces effective bone formation from reversibly immortalized multipotent adipose-derived (iMAD) mesenchymal stem cells.
Lu S, Wang J, Ye J, Zou Y, Zhu Y, Wei Q, Wang X, Tang S, Liu H, Fan J, Zhang F, Farina EM, Mohammed MM, Song D, Liao J, Huang J, Guo D, Lu M, Liu F, Liu J, Li L, Ma C, Hu X, Lee MJ, Reid RR, Ameer GA, Zhou D, He T. Lu S, et al. Among authors: ma c. Am J Transl Res. 2016 Sep 15;8(9):3710-3730. eCollection 2016. Am J Transl Res. 2016. PMID: 27725853 Free PMC article.
Engineering the Rapid Adenovirus Production and Amplification (RAPA) Cell Line to Expedite the Generation of Recombinant Adenoviruses.
Wei Q, Fan J, Liao J, Zou Y, Song D, Liu J, Cui J, Liu F, Ma C, Hu X, Li L, Yu Y, Qu X, Chen L, Yu X, Zhang Z, Zhao C, Zeng Z, Zhang R, Yan S, Wu X, Shu Y, Reid RR, Lee MJ, Wolf JM, He TC. Wei Q, et al. Among authors: ma c. Cell Physiol Biochem. 2017;41(6):2383-2398. doi: 10.1159/000475909. Epub 2017 May 3. Cell Physiol Biochem. 2017. PMID: 28463838 Free article.
lncRNA H19 mediates BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) through Notch signaling.
Liao J, Yu X, Hu X, Fan J, Wang J, Zhang Z, Zhao C, Zeng Z, Shu Y, Zhang R, Yan S, Li Y, Zhang W, Cui J, Ma C, Li L, Yu Y, Wu T, Wu X, Lei J, Wang J, Yang C, Wu K, Wu Y, Tang J, He BC, Deng ZL, Luu HH, Haydon RC, Reid RR, Lee MJ, Wolf JM, Huang W, He TC. Liao J, et al. Among authors: ma c. Oncotarget. 2017 Jun 27;8(32):53581-53601. doi: 10.18632/oncotarget.18655. eCollection 2017 Aug 8. Oncotarget. 2017. PMID: 28881833 Free PMC article.
Monensin inhibits cell proliferation and tumor growth of chemo-resistant pancreatic cancer cells by targeting the EGFR signaling pathway.
Wang X, Wu X, Zhang Z, Ma C, Wu T, Tang S, Zeng Z, Huang S, Gong C, Yuan C, Zhang L, Feng Y, Huang B, Liu W, Zhang B, Shen Y, Luo W, Wang X, Liu B, Lei Y, Ye Z, Zhao L, Cao D, Yang L, Chen X, Haydon RC, Luu HH, Peng B, Liu X, He TC. Wang X, et al. Among authors: ma c. Sci Rep. 2018 Dec 17;8(1):17914. doi: 10.1038/s41598-018-36214-5. Sci Rep. 2018. PMID: 30559409 Free PMC article.
Notch Signaling Augments BMP9-Induced Bone Formation by Promoting the Osteogenesis-Angiogenesis Coupling Process in Mesenchymal Stem Cells (MSCs).
Liao J, Wei Q, Zou Y, Fan J, Song D, Cui J, Zhang W, Zhu Y, Ma C, Hu X, Qu X, Chen L, Yu X, Zhang Z, Wang C, Zhao C, Zeng Z, Zhang R, Yan S, Wu T, Wu X, Shu Y, Lei J, Li Y, Luu HH, Lee MJ, Reid RR, Ameer GA, Wolf JM, He TC, Huang W. Liao J, et al. Among authors: ma c. Cell Physiol Biochem. 2017;41(5):1905-1923. doi: 10.1159/000471945. Epub 2017 Apr 4. Cell Physiol Biochem. 2017. PMID: 28384643 Free article.
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