Tokiwa H - Search Results

1

A Novel Potent and Highly Specific Inhibitor against Influenza Viral N1-N9 Neuraminidases: Insight into Neuraminidase-Inhibitor Interactions.

Sriwilaijaroen N, Magesh S, Imamura A, Ando H, Ishida H, Sakai M, Ishitsubo E, Hori T, Moriya S, Ishikawa T, Kuwata K, Odagiri T, Tashiro M, Hiramatsu H, Tsukamoto K, Miyagi T, Tokiwa H, Kiso M, Suzuki Y. Sriwilaijaroen N, et al. Among authors: tokiwa h. J Med Chem. 2016 May 26;59(10):4563-77. doi: 10.1021/acs.jmedchem.5b01863. Epub 2016 May 4. J Med Chem. 2016. PMID: 27095056

2

Structure-anti-MRSA activity relationship of macrocyclic bis(bibenzyl) derivatives.

Sawada H, Onoda K, Morita D, Ishitsubo E, Matsuno K, Tokiwa H, Kuroda T, Miyachi H. Sawada H, et al. Among authors: tokiwa h. Bioorg Med Chem Lett. 2013 Dec 15;23(24):6563-8. doi: 10.1016/j.bmcl.2013.10.069. Epub 2013 Nov 6. Bioorg Med Chem Lett. 2013. PMID: 24239015

3

Structure-activity relationship of novel menaquinone-4 analogues: modification of the side chain affects their biological activities.

Suhara Y, Hanada N, Okitsu T, Sakai M, Watanabe M, Nakagawa K, Wada A, Takeda K, Takahashi K, Tokiwa H, Okano T. Suhara Y, et al. Among authors: tokiwa h. J Med Chem. 2012 Feb 23;55(4):1553-8. doi: 10.1021/jm2013166. Epub 2012 Feb 7. J Med Chem. 2012. PMID: 22250752

4

RXR partial agonist produced by side chain repositioning of alkoxy RXR full agonist retains antitype 2 diabetes activity without the adverse effects.

Kawata K, Morishita K, Nakayama M, Yamada S, Kobayashi T, Furusawa Y, Arimoto-Kobayashi S, Oohashi T, Makishima M, Naitou H, Ishitsubo E, Tokiwa H, Tai A, Kakuta H. Kawata K, et al. Among authors: tokiwa h. J Med Chem. 2015 Jan 22;58(2):912-26. doi: 10.1021/jm501863r. Epub 2014 Dec 17. J Med Chem. 2015. PMID: 25486327

5

Origin of Stereoselectivity and Substrate/Ligand Recognition in an FAD-Dependent R-Selective Amine Oxidase.

Nakano S, Yasukawa K, Tokiwa T, Ishikawa T, Ishitsubo E, Matsuo N, Ito S, Tokiwa H, Asano Y. Nakano S, et al. Among authors: tokiwa t, tokiwa h. J Phys Chem B. 2016 Oct 20;120(41):10736-10743. doi: 10.1021/acs.jpcb.6b09328. Epub 2016 Oct 10. J Phys Chem B. 2016. PMID: 27648606

6

Ab initio fragment molecular orbital studies of influenza virus hemagglutinin-sialosaccharide complexes toward chemical clarification about the virus host range determination.

Sawada T, Hashimoto T, Tokiwa H, Suzuki T, Nakano H, Ishida H, Kiso M, Suzuki Y. Sawada T, et al. Among authors: tokiwa h. Glycoconj J. 2008 Dec;25(9):805-15. doi: 10.1007/s10719-008-9141-9. Epub 2008 Jun 24. Glycoconj J. 2008. PMID: 18574690

7

Trifluoromethanesulfonyloxy-group-directed regioselective (3 + 2) cycloadditions of benzynes for the synthesis of functionalized benzo-fused heterocycles.

Ikawa T, Kaneko H, Masuda S, Ishitsubo E, Tokiwa H, Akai S. Ikawa T, et al. Among authors: tokiwa h. Org Biomol Chem. 2015 Jan 14;13(2):520-6. doi: 10.1039/c4ob01627k. Org Biomol Chem. 2015. PMID: 25378144

8

Ab initio base fragment molecular orbital studies of influenza viral hemagglutinin HA1 full-domains in complex with sialoside receptors.

Sawada T, Hashimoto T, Tokiwa H, Suzuki T, Nakano H, Ishida H, Kiso M, Suzuki Y. Sawada T, et al. Among authors: tokiwa h. J Mol Genet Med. 2008 Nov 26;3(1):133-42. J Mol Genet Med. 2008. PMID: 19565017 Free PMC article.

9

Amino acid substitutions contributing to α2,6-sialic acid linkage binding specificity of human parainfluenza virus type 3 hemagglutinin-neuraminidase.

Fukushima K, Takahashi T, Ueyama H, Takaguchi M, Ito S, Oishi K, Minami A, Ishitsubo E, Tokiwa H, Takimoto T, Suzuki T. Fukushima K, et al. Among authors: tokiwa h. FEBS Lett. 2015 May 8;589(11):1278-82. doi: 10.1016/j.febslet.2015.03.036. Epub 2015 Apr 11. FEBS Lett. 2015. PMID: 25871520 Free PMC article.

10

Comparative Binding Analysis of Dipeptidyl Peptidase IV (DPP-4) with Antidiabetic Drugs - An Ab Initio Fragment Molecular Orbital Study.

Arulmozhiraja S, Matsuo N, Ishitsubo E, Okazaki S, Shimano H, Tokiwa H. Arulmozhiraja S, et al. Among authors: tokiwa h. PLoS One. 2016 Nov 10;11(11):e0166275. doi: 10.1371/journal.pone.0166275. eCollection 2016. PLoS One. 2016. PMID: 27832184 Free PMC article.

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