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A pharmacokinetic-pharmacodynamic model for intrathecal baclofen in patients with severe spasticity.
Br J Clin Pharmacol. 2016 Jan;81(1):101-12. doi: 10.1111/bcp.12781.
Br J Clin Pharmacol. 2016.
PMID: 27099877
Free PMC article.
Clinical relevance of pharmacological and physiological data in intrathecal baclofen therapy.
Heetla HW, Staal MJ, Proost JH, van Laar T.
Heetla HW, et al.
Arch Phys Med Rehabil. 2014 Nov;95(11):2199-206. doi: 10.1016/j.apmr.2014.04.030. Epub 2014 Jun 2.
Arch Phys Med Rehabil. 2014.
PMID: 24893275
Review.
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Improved gait performance in a patient with hereditary spastic paraplegia after a continuous intrathecal baclofen test infusion and subsequent pump implantation: a case report.
Heetla HW, Halbertsma JP, Dekker R, Staal MJ, van Laar T.
Heetla HW, et al.
Arch Phys Med Rehabil. 2015 Jun;96(6):1166-9. doi: 10.1016/j.apmr.2015.01.012. Epub 2015 Jan 24.
Arch Phys Med Rehabil. 2015.
PMID: 25626112
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The incidence and management of tolerance in intrathecal baclofen therapy.
Heetla HW, Staal MJ, Kliphuis C, van Laar T.
Heetla HW, et al.
Spinal Cord. 2009 Oct;47(10):751-6. doi: 10.1038/sc.2009.34. Epub 2009 Mar 31.
Spinal Cord. 2009.
PMID: 19333246
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Tolerance to continuous intrathecal baclofen infusion can be reversed by pulsatile bolus infusion.
Heetla HW, Staal MJ, van Laar T.
Heetla HW, et al.
Spinal Cord. 2010 Jun;48(6):483-6. doi: 10.1038/sc.2009.156. Epub 2009 Nov 17.
Spinal Cord. 2010.
PMID: 19918253
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