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SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.
Kim D, Fiske BP, Birsoy K, Freinkman E, Kami K, Possemato RL, Chudnovsky Y, Pacold ME, Chen WW, Cantor JR, Shelton LM, Gui DY, Kwon M, Ramkissoon SH, Ligon KL, Kang SW, Snuderl M, Vander Heiden MG, Sabatini DM. Kim D, et al. Among authors: kami k. Nature. 2015 Apr 16;520(7547):363-7. doi: 10.1038/nature14363. Epub 2015 Apr 8. Nature. 2015. PMID: 25855294 Free PMC article.
Arginine Deprivation Inhibits the Warburg Effect and Upregulates Glutamine Anaplerosis and Serine Biosynthesis in ASS1-Deficient Cancers.
Kremer JC, Prudner BC, Lange SES, Bean GR, Schultze MB, Brashears CB, Radyk MD, Redlich N, Tzeng SC, Kami K, Shelton L, Li A, Morgan Z, Bomalaski JS, Tsukamoto T, McConathy J, Michel LS, Held JM, Van Tine BA. Kremer JC, et al. Among authors: kami k. Cell Rep. 2017 Jan 24;18(4):991-1004. doi: 10.1016/j.celrep.2016.12.077. Cell Rep. 2017. PMID: 28122247 Free PMC article.
Mycoplasma infection and hypoxia initiate succinate accumulation and release in the VM-M3 cancer cells.
Flores RE, Brown AK, Taus L, Khoury J, Glover F, Kami K, Sarangarajan R, Walshe TE, Narain NR, Kiebish MA, Shelton LM, Chinopoulos C, Seyfried TN. Flores RE, et al. Among authors: kami k. Biochim Biophys Acta Bioenerg. 2018 Sep;1859(9):975-983. doi: 10.1016/j.bbabio.2018.03.012. Epub 2018 Mar 23. Biochim Biophys Acta Bioenerg. 2018. PMID: 29580805 Free article.
131 results