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High Affinity Agonists of the Neuropeptide Y (NPY) Y4 Receptor Derived from the C-Terminal Pentapeptide of Human Pancreatic Polypeptide (hPP): Synthesis, Stereochemical Discrimination, and Radiolabeling.
J Med Chem. 2016 Jul 14;59(13):6045-58. doi: 10.1021/acs.jmedchem.6b00309. Epub 2016 Jun 22.
J Med Chem. 2016.
PMID: 27223253
N(ω)-Carbamoylation of the Argininamide Moiety: An Avenue to Insurmountable NPY Y1 Receptor Antagonists and a Radiolabeled Selective High-Affinity Molecular Tool ([(3)H]UR-MK299) with Extended Residence Time.
Keller M, Weiss S, Hutzler C, Kuhn KK, Mollereau C, Dukorn S, Schindler L, Bernhardt G, König B, Buschauer A.
Keller M, et al. Among authors: dukorn s.
J Med Chem. 2015 Nov 25;58(22):8834-49. doi: 10.1021/acs.jmedchem.5b00925. Epub 2015 Nov 4.
J Med Chem. 2015.
PMID: 26466164
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Fluorescence- and Radiolabeling of [Lys4,Nle17,30]hPP Yields Molecular Tools for the NPY Y4 Receptor.
Dukorn S, Littmann T, Keller M, Kuhn K, Cabrele C, Baumeister P, Bernhardt G, Buschauer A.
Dukorn S, et al.
Bioconjug Chem. 2017 Apr 19;28(4):1291-1304. doi: 10.1021/acs.bioconjchem.7b00103. Epub 2017 Apr 5.
Bioconjug Chem. 2017.
PMID: 28345900
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In Search of NPY Y4R Antagonists: Incorporation of Carbamoylated Arginine, Aza-Amino Acids, or d-Amino Acids into Oligopeptides Derived from the C-Termini of the Endogenous Agonists.
Kuhn KK, Littmann T, Dukorn S, Tanaka M, Keller M, Ozawa T, Bernhardt G, Buschauer A.
Kuhn KK, et al. Among authors: dukorn s.
ACS Omega. 2017 Jul 31;2(7):3616-3631. doi: 10.1021/acsomega.7b00451. Epub 2017 Jul 14.
ACS Omega. 2017.
PMID: 30023699
Free PMC article.
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