Grempler R - Search Results

1

Short- and Longterm Glycemic Control of Streptozotocin-Induced Diabetic Rats Using Different Insulin Preparations.

Luippold G, Bedenik J, Voigt A, Grempler R. Luippold G, et al. Among authors: grempler r. PLoS One. 2016 Jun 2;11(6):e0156346. doi: 10.1371/journal.pone.0156346. eCollection 2016. PLoS One. 2016. PMID: 27253523 Free PMC article.

2

Empagliflozin, a novel potent and selective SGLT-2 inhibitor, improves glycaemic control alone and in combination with insulin in streptozotocin-induced diabetic rats, a model of type 1 diabetes mellitus.

Luippold G, Klein T, Mark M, Grempler R. Luippold G, et al. Among authors: grempler r. Diabetes Obes Metab. 2012 Jul;14(7):601-7. doi: 10.1111/j.1463-1326.2012.01569.x. Epub 2012 Feb 23. Diabetes Obes Metab. 2012. PMID: 22268612

3

Characterization of Micro-RNA Changes during the Progression of Type 2 Diabetes in Zucker Diabetic Fatty Rats.

Delic D, Eisele C, Schmid R, Luippold G, Mayoux E, Grempler R. Delic D, et al. Among authors: grempler r. Int J Mol Sci. 2016 May 3;17(5):665. doi: 10.3390/ijms17050665. Int J Mol Sci. 2016. PMID: 27153060 Free PMC article.

4

Discovery and translation of a target engagement marker for AMP-activated protein kinase (AMPK).

Grempler R, Wolff M, Simon E, Schmid R, Eisele C, Rieber K, Fischer E, Mettel S, Gabrielyan O, Delic D, Luippold G, Redeman N. Grempler R, et al. PLoS One. 2018 May 25;13(5):e0197849. doi: 10.1371/journal.pone.0197849. eCollection 2018. PLoS One. 2018. PMID: 29799853 Free PMC article.

5

Normalization of prandial blood glucose and improvement of glucose tolerance by liver-specific inhibition of SH2 domain containing inositol phosphatase 2 (SHIP2) in diabetic KKAy mice: SHIP2 inhibition causes insulin-mimetic effects on glycogen metabolism, gluconeogenesis, and glycolysis.

Grempler R, Zibrova D, Schoelch C, van Marle A, Rippmann JF, Redemann N. Grempler R, et al. Diabetes. 2007 Sep;56(9):2235-41. doi: 10.2337/db06-1660. Epub 2007 Jun 27. Diabetes. 2007. PMID: 17596404

6

Long-term treatment with empagliflozin, a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats.

Thomas L, Grempler R, Eckhardt M, Himmelsbach F, Sauer A, Klein T, Eickelmann P, Mark M. Thomas L, et al. Among authors: grempler r. Diabetes Obes Metab. 2012 Jan;14(1):94-6. doi: 10.1111/j.1463-1326.2011.01518.x. Epub 2011 Nov 13. Diabetes Obes Metab. 2012. PMID: 21985693

7

Inhibition of the interaction between protein phosphatase 1 glycogen-targeting subunit and glycogen phosphorylase increases glycogen synthesis in primary rat hepatocytes.

Zibrova D, Grempler R, Streicher R, Kauschke SG. Zibrova D, et al. Among authors: grempler r. Biochem J. 2008 Jun 1;412(2):359-66. doi: 10.1042/BJ20071483. Biochem J. 2008. PMID: 18298402

8

Empagliflozin, a novel selective sodium glucose cotransporter-2 (SGLT-2) inhibitor: characterisation and comparison with other SGLT-2 inhibitors.

Grempler R, Thomas L, Eckhardt M, Himmelsbach F, Sauer A, Sharp DE, Bakker RA, Mark M, Klein T, Eickelmann P. Grempler R, et al. Diabetes Obes Metab. 2012 Jan;14(1):83-90. doi: 10.1111/j.1463-1326.2011.01517.x. Epub 2011 Nov 13. Diabetes Obes Metab. 2012. PMID: 21985634

9

Combination of the sodium-glucose cotransporter-2 inhibitor empagliflozin with orlistat or sibutramine further improves the body-weight reduction and glucose homeostasis of obese rats fed a cafeteria diet.

Vickers SP, Cheetham SC, Headland KR, Dickinson K, Grempler R, Mayoux E, Mark M, Klein T. Vickers SP, et al. Among authors: grempler r. Diabetes Metab Syndr Obes. 2014 Jul 1;7:265-75. doi: 10.2147/DMSO.S58786. eCollection 2014. Diabetes Metab Syndr Obes. 2014. PMID: 25061325 Free PMC article.

10

Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study.

Bizzotto R, Jennison C, Jones AG, Kurbasic A, Tura A, Kennedy G, Bell JD, Thomas EL, Frost G, Eriksen R, Koivula RW, Brage S, Kaye J, Hattersley AT, Heggie A, McEvoy D, 't Hart LM, Beulens JW, Elders P, Musholt PB, Ridderstråle M, Hansen TH, Allin KH, Hansen T, Vestergaard H, Lundgaard AT, Thomsen HS, De Masi F, Tsirigos KD, Brunak S, Viñuela A, Mahajan A, McDonald TJ, Kokkola T, Forgie IM, Giordano GN, Pavo I, Ruetten H, Dermitzakis E, McCarthy MI, Pedersen O, Schwenk JM, Adamski J, Franks PW, Walker M, Pearson ER, Mari A; IMI DIRECT consortium. Bizzotto R, et al. Diabetes Care. 2021 Feb;44(2):511-518. doi: 10.2337/dc20-1567. Epub 2020 Dec 15. Diabetes Care. 2021. PMID: 33323478

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